Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25098774 | 1.00 | MLYCD (0.33) | MLYCDMAPTPIK3CDRECQL | |
| SCHEMBL25098446 | 0.76 | — | — | |
| SCHEMBL20624707 | 0.73 | DUT (0.33) | PIK3CDRECQL | |
| SCHEMBL10175141 | 0.72 | MLYCD (0.38) | MLYCDMAPT | |
| SCHEMBL1754047 | 0.71 | EPHX1 (0.41) | PIK3CD | |
| SCHEMBL12951505 | 0.68 | PIK3CD (0.35) | PIK3CD | |
| SCHEMBL18347932 | 0.68 | HRH3 (0.32) | — | |
| SCHEMBL13401126 | 0.67 | MAPT (0.37) | MLYCDMAPT | |
| SCHEMBL14818736 | 0.67 | ALDH1A1 (0.34) | RECQL | |
| SCHEMBL25443684 | 0.66 | PIK3CD (0.50) | MLYCDMAPTPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230077316-A1 | CTPS1 INHIBITORS AND USES THEREOF | NIMBUS DISCOVERY, INC. | 2023-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230077316-A1 | CTPS1 INHIBITORS AND USES THEREOF | CTPS1, CTPS2, ECHS1 | MLYCD 433/4885MAPT 2064/4885PIK3CD 1870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.