Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSL1 | P33121 | 2/20 | 0.49 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894070 | 0.96 | ACSL1 (0.45) | ACSL1ACSL6PPARAKCNA3PDK2 | |
| SCHEMBL9423929 | 0.87 | ACSL1 (0.50) | ACSL1ACSL6PPARAKCNA3PDK2 | |
| SCHEMBL23091409 | 0.73 | KCNA3 (0.42) | PPARAKCNA3PPARGPPARDFFAR1 | |
| SCHEMBL23091410 | 0.73 | KCNA3 (0.42) | PPARAKCNA3PPARGPPARDFFAR1 | |
| SCHEMBL15237264 | 0.72 | GAA (0.56) | — | |
| SCHEMBL9423885 | 0.71 | MAOA (0.51) | TSHRPPARGPPARDFFAR1MAOA | |
| SCHEMBL10722424 | 0.70 | HDAC1 (0.68) | ACSL1ACSL6PPARAPDK2FFAR1 | |
| SCHEMBL2277251 | 0.69 | MAOB (0.50) | MAOAMAOB | |
| SCHEMBL6566874 | 0.69 | L3MBTL1 (0.50) | — | |
| SCHEMBL1162023 | 0.69 | PPARA (0.74) | PPARAKCNA3FFAR1SERPINE1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034900-B2 | Water-soluble thioester and selenoester compounds and methods for making and using the same | AMYLIN PHARMACEUTICALS, INC. (US) | 2011-10-11 | — | — | US | disclosed |
| EP-1631597-A4 | DISPLACEABLE LINKER SOLID PHASE CHEMICAL LIGATION | GRYPHON THERAPEUTICS INC (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1616003-A4 | WATER-SOLUBLE THIOESTER AND SELENOESTER COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | GRYPHON THERAPEUTICS INC (US) | 2007-06-20 | — | — | EP | disclosed |
| EP-1616021-A4 | MULTIPLEX POLYMER LIGATION | GRYPHON THERAPEUTICS INC (US) | 2006-08-30 | — | — | EP | disclosed |
| US-20060173159-A1 | Water-soluble thioester and selenoester compounds and methods for making and using the same | ASTRAZENECA PHARMACEUTICALS LP | 2006-08-03 | — | — | US | disclosed |
| EP-1631597-A2 | DISPLACEABLE LINKER SOLID PHASE CHEMICAL LIGATION | Gryphon Therapeutics, Inc. (US) | 2006-03-08 | — | — | EP | disclosed |
| EP-1616021-A2 | MULTIPLEX POLYMER LIGATION | Gryphon Therapeutics, Inc. (US) | 2006-01-18 | — | — | EP | disclosed |
| EP-1616003-A1 | WATER-SOLUBLE THIOESTER AND SELENOESTER COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | Gryphon Therapeutics, Inc. (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004105685-A2 | DISPLACEABLE LINKER SOLID PHASE CHEMICAL LIGATION | GRYPHON THERAPEUTICS, INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| WO-2004061094-A1 | WATER-SOLUBLE THIOESTER AND SELENOESTER COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | GRYPHON THERAPEUTICS, INC. (US) | 2004-07-22 | — | — | WO | disclosed |
| WO-2004060863-A2 | BACKBONE ANCHORED THIOESTER AND SELENOESTER GENERATORS | GRYPHON THERAPEUTICS, INC. (US) | 2004-07-22 | — | — | WO | disclosed |
| WO-2004060925-A2 | MULTIPLEX POLYMER LIGATION | GRYPHON THERAPEUTICS, INC. (US) | 2004-07-22 | — | — | WO | disclosed |
| US-20040132966-A1 | Backbone anchored thioester and selenoester generators | GRYPHON THERAPEUTICS, INC. | 2004-07-08 | — | — | US | disclosed |
| US-20040063902-A1 | Side chain anchored thioester and selenoester generators | GRYPHON THERAPEUTICS, INC. | 2004-04-01 | — | — | US | disclosed |
| WO-2004011424-A2 | SIDE CHAIN ANCHORED THIOESTER AND SELENOESTER GENERATORS | GRYPHON THERAPEUTICS, INC. (US) | 2004-02-05 | — | — | WO | disclosed |
| US-6566494-B1 | Solid support for use in the generation of preferential peptides | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2003-05-20 | — | — | US | disclosed |
| US-5917015-A | Support material for solid phase organic synthesis | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1999-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132966-A1 | Backbone anchored thioester and selenoester generators | SCLY, SELENOI, ETF1 | ACSL1 512/4885ACSL6 148/4885PPARA 3749/4885 |
| US-20060173159-A1 | Water-soluble thioester and selenoester compounds and methods for making and using the same | SCLY, TST, SELENOI | ACSL1 403/4885ACSL6 139/4885PPARA 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.