Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12205513 | 0.84 | NR3C1 (0.54) | L3MBTL1CYP2C9CYP1A2CYP2C19NR3C1 | |
| SCHEMBL2952247 | 0.81 | CA2 (0.50) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL29438813 | 0.80 | CYP2C9 (0.61) | L3MBTL1CYP2C9CYP1A2CYP2C19NR3C1 | |
| SCHEMBL27694186 | 0.78 | L3MBTL1 (0.45) | L3MBTL1CYP2C9CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL18648400 | 0.77 | L3MBTL1 (0.43) | L3MBTL1CYP2C9CYP1A2CYP2C19NR3C1 | |
| SCHEMBL16450352 | 0.77 | CYP3A4 (0.43) | L3MBTL1NR3C1MAPTKMT2ALMNA | |
| SCHEMBL29326329 | 0.75 | L3MBTL1 (0.44) | L3MBTL1CYP2C9CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL15237264 | 0.75 | GAA (0.56) | NR3C1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL29413779 | 0.73 | MAOA (0.58) | CYP2C9NR3C1MAPTKMT2ALMNA | |
| SCHEMBL88261 | 0.73 | MAOA (0.58) | CYP2C9NR3C1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242854-A1 | Chemical capture reagent | GE HEALTHCARE UK LIMITED (GB) | 2004-12-02 | — | — | US | claimed |
| EP-1402268-A2 | CHEMICAL CAPTURE REAGENT | Amersham Biosciences UK Limited (GB) | 2004-03-31 | — | — | EP | claimed |
| WO-2003005026-A2 | CHEMICAL CAPTURE REAGENT | AMERSHAM BIOSCIENCES UK LIMITED (GB) | 2003-01-16 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242854-A1 | Chemical capture reagent | SPPL2B, PRXL2A, PLG | L3MBTL1 3390/4885CYP2C9 1632/4885CYP1A2 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.