Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | BLVRB | P30043 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25128679 | 0.90 | CYP26A1 (0.34) | MEN1CYP26A1PGRCYP3A4ADORA3 | |
| SCHEMBL29292671 | 0.82 | CNR1 (0.32) | — | |
| SCHEMBL25126829 | 0.81 | CYP26A1 (0.32) | MEN1CYP26A1PGRCYP3A4ADORA3 | |
| SCHEMBL25128120 | 0.80 | KDM4E (0.32) | — | |
| SCHEMBL25128111 | 0.80 | KIF11 (0.30) | — | |
| SCHEMBL25126778 | 0.78 | RXRA (0.32) | CYP26A1 | |
| SCHEMBL23444328 | 0.78 | RARA (0.39) | JAK2JAK3MEN1CYP26A1PGR | |
| SCHEMBL22795138 | 0.78 | — | — | |
| SCHEMBL26625478 | 0.76 | CYP1A2 (0.33) | — | |
| SCHEMBL23445678 | 0.75 | RARA (0.40) | JAK2JAK3MEN1CYP26A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230096132-A1 | CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2023-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230096132-A1 | CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND | LAGE3, ELOC, ELOB | JAK2 4114/4885JAK3 4302/4885MEN1 3848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.