SCHEMBL4624622

SCHEMBL4624622

Cc1ccc2c(c1)N(C)c1ccc(C)cc1N2C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 1/20 0.41
CYP2A6 P11509 3/20 0.41
CYP1A2 P05177 2/20 0.41
HSD17B10 Q99714 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
ALDH1A1 P00352 3/20 0.38
TDP1 Q9NUW8 5/20 0.37
ACHE P22303 2/20 0.37
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
PKM P14618 1/20 0.37
CNR1 P21554 1/20 0.37
GPR55 Q9Y2T6 1/20 0.37
TP53 P04637 2/20 0.36
CYP3A4 P08684 1/20 0.36
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17339860 1.00 TERT (0.41) TERTCYP2A6CYP1A2HSD17B10NPSR1
SCHEMBL12901940 0.93 MAOA (0.43) TERTCYP2A6CYP1A2HSD17B10TDP1
SCHEMBL10170807 0.83 ACHE (0.46) ALDH1A1ACHEKDM4EMEN1MAPT
SCHEMBL7270780 0.83 TSHR (0.46) TERTHSD17B10ALDH1A1TDP1KDM4E
SCHEMBL7263176 0.83 PSMB5 (0.42) TERTNPSR1ALDH1A1KDM4EMEN1
SCHEMBL25137403 0.82 HTT (0.41) TERTCYP2A6CYP1A2HSD17B10NPSR1
SCHEMBL7263868 0.82 ALDH1A1 (0.41) TERTCYP2A6CYP1A2HSD17B10NPSR1
SCHEMBL12841526 0.80 OPRK1 (0.40) TERTCYP1A2HSD17B10NPSR1ALDH1A1
SCHEMBL10274619 0.80 HSD17B10 (0.48) HSD17B10NPSR1ALDH1A1KMT2APKM
SCHEMBL10072419 0.76 OPRK1 (0.43) TERTCYP1A2HSD17B10NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210240047-A1 ELECTROCHROMIC COMPOUNDS GENTEX CORPORATION (US) 2021-08-05 US disclosed
EP-1234211-B1 ELECTROACTIVE MATERIALS AND BENEFICIAL AGENTS HAVING A SOLUBLIZING MOIETY GENTEX CORP (US) 2017-02-15 EP disclosed
US-9214634-B2 Organic photovoltaic cell, organic semiconductor polymer and composition for organic semiconductor material used therefor FUJIFILM CORPORATION (JP) 2015-12-15 US disclosed
US-9214634-B2 Organic photovoltaic cell, organic semiconductor polymer and composition for organic semiconductor material used therefor FUJIFILM CORPORATION (JP) 2015-12-15 US disclosed
EP-1234211-A4 ELECTROACTIVE MATERIALS AND BENEFICIAL AGENTS HAVING A SOLUBLIZING MOIETY GENTEX CORP (US) 2008-04-23 EP disclosed
US-6661559-B2 Transparent substrate having an electrically conductive material; redox electroactive compounds; colorimetric analysis GENTEX CORPORATION 2003-12-09 US disclosed
US-6445486-B1 Electroactive materials and beneficial agents having a solubilizing moiety GENTEX CORPORATION 2002-09-03 US disclosed
EP-1234211-A2 ELECTROACTIVE MATERIALS AND BENEFICIAL AGENTS HAVING A SOLUBLIZING MOIETY Gentex Corporation (US) 2002-08-28 EP disclosed
US-20020051278-A1 Electrochromic media for producing a preselected color and devices comprising same BYKER HARLAN J (US) 2002-05-02 US disclosed
US-6288825-B1 Electrochromic media for producing a preselected color and devices comprising same GENTEX CORPORATION 2001-09-11 US disclosed
WO-2001040858-A1 ELECTROACTIVE MATERIALS AND BENEFICIAL AGENTS HAVING A SOLUBLIZING MOIETY GENTEX CORPORATION (US) 2001-06-07 WO disclosed
US-6141137-A Electrochromic media for producing a preselected color GENTEX CORPORATION (US) 2000-10-31 US disclosed