Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13851149 | 0.80 | MET (0.60) | ALDH1A1SMN1; SMN2METTNKS2CYP3A4 | |
| SCHEMBL4472398 | 0.80 | PDE7A (0.52) | ALDH1A1TNKS2CYP3A4KDM4EPDE4B | |
| SCHEMBL13870581 | 0.77 | MET (0.54) | ALDH1A1SMN1; SMN2METTNKS2CYP3A4 | |
| SCHEMBL30251689 | 0.77 | TUBB4A (0.48) | ALDH1A1SMN1; SMN2METTNKS2PDE4B | |
| SCHEMBL27448400 | 0.77 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2METTNKS2CYP3A4 | |
| SCHEMBL6481775 | 0.75 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2CYP3A4KDM4EPTGS1 | |
| SCHEMBL5666942 | 0.74 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2CYP3A4KDM4EIDH1 | |
| SCHEMBL25140419 | 0.74 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2CYP3A4KDM4EMAPT | |
| SCHEMBL13857452 | 0.73 | ALOX5 (0.54) | ALDH1A1METTNKS2KDM4EMAPT | |
| SCHEMBL23743671 | 0.73 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2METTNKS2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023061457-A1 | ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF | 百奥泰生物制药股份有限公司 | 2023-04-20 | — | — | WO | disclosed |