SCHEMBL25144541

SCHEMBL25144541

CC(C)CCC(=O)NCC(COC(C)C)OC=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TLR2 O60603 2/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ FOLH1 Q04609 1/20 0.33
▸ HPGD P15428 1/20 0.30
▸ CA1 P00915 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25144691 0.84 TLR2 (0.38) TLR2ALDH1A1
SCHEMBL25144693 0.78 TLR2 (0.32) TLR2ALDH1A1
SCHEMBL25144632 0.72 ADH1B (0.30) —
SCHEMBL13933835 0.71 TLR2 (0.35) TLR2HPGD
SCHEMBL9349283 0.70 CYP2D6 (0.52) ALDH1A1HPGDCA1
SCHEMBL20438450 0.68 TLR2 (0.36) TLR2ALDH1A1
SCHEMBL19818505 0.68 ALDH1A1 (0.44) ALDH1A1HPGDCA1
SCHEMBL16472222 0.67 LMNA (0.32) TLR2
SCHEMBL20717791 0.66 — —
SCHEMBL14389198 0.66 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230119227-A1 OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT INTEGRATED DNA TECHNOLOGIES, INC. 2023-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230119227-A1 OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT RNGTT, SSU72, NSUN2 TLR2 3267/4885ALDH1A1 3898/4885FOLH1 994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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