SCHEMBL25144643

SCHEMBL25144643

CC(C)NCC(COC(C)SS)OC(=O)C(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ ADRB2 P07550 4/20 0.31
▸ ADRB1 P08588 4/20 0.31
▸ ADRB3 P13945 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25144825 0.84 ADRB2 (0.34) ADRB2ADRB1ADRB3
SCHEMBL25144721 0.84 ADRB2 (0.34) ADRB2ADRB1ADRB3
SCHEMBL25144620 0.71 — —
SCHEMBL19034592 0.67 ADRB2 (0.37) ADRB2ADRB1ADRB3
SCHEMBL25144538 0.67 TSHR (0.33) ADRB2ADRB1ADRB3
SCHEMBL25144614 0.66 TSHR (0.40) ADRB2ADRB1ADRB3
SCHEMBL25144693 0.63 TLR2 (0.32) —
SCHEMBL12285560 0.60 TSHR (0.53) ADRB2ADRB1ADRB3
SCHEMBL12285485 0.60 TSHR (0.53) ADRB2ADRB1ADRB3
SCHEMBL2438756 0.60 LMNA (0.34) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230119227-A1 OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT INTEGRATED DNA TECHNOLOGIES, INC. 2023-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230119227-A1 OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT RNGTT, SSU72, NSUN2 ADRB2 4792/4885ADRB1 4770/4885ADRB3 4815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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