SCHEMBL25144825

SCHEMBL25144825

CC(C)NCC(COC(C)C)OC(=O)C(Cl)Cl

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ ADRB2 P07550 12/20 0.34
▸ ADRB1 P08588 12/20 0.34
▸ ADRB3 P13945 12/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25144721 1.00 ADRB2 (0.34) ADRB2ADRB1ADRB3
SCHEMBL25144620 0.87 — —
SCHEMBL25144643 0.84 ADRB2 (0.31) ADRB2ADRB1ADRB3
SCHEMBL25144614 0.81 TSHR (0.40) ADRB2ADRB1ADRB3
SCHEMBL25144693 0.77 TLR2 (0.32) —
SCHEMBL19034592 0.73 ADRB2 (0.37) ADRB2ADRB1ADRB3
SCHEMBL19542989 0.71 ADRB2 (0.31) ADRB2ADRB1ADRB3
SCHEMBL22278963 0.70 ADRB2 (0.31) ADRB2ADRB1ADRB3
SCHEMBL25144632 0.69 ADH1B (0.30) —
SCHEMBL25144538 0.69 TSHR (0.33) ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230119227-A1 OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT INTEGRATED DNA TECHNOLOGIES, INC. 2023-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230119227-A1 OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT RNGTT, SSU72, NSUN2 ADRB2 4792/4885ADRB1 4770/4885ADRB3 4815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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