SCHEMBL25158902

SCHEMBL25158902

Cc1c(C(C)C)cc([Si](C)(C)C)cc1C(C)C

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.32
TRPA1 O75762 1/20 0.32
CHRM1 P11229 1/20 0.32
SLC6A2 P23975 1/20 0.32
ADRA1A P35348 1/20 0.32
HTR2B P41595 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
GABRA1 P14867 3/20 0.30
GABRB1 P18505 3/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25763000 0.89 LMNA (0.31) LMNA
SCHEMBL26560637 0.87 CA1 (0.41) CA1CA2
SCHEMBL26560642 0.79 CA1 (0.39) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL28839082 0.78 CA1 (0.58) LMNASLC6A2HTR2BCA1CA2
SCHEMBL29132817 0.76 CA1 (0.56) LMNASLC6A2HTR2BCA1CA2
Lithium SCHEMBL30621947 0.76 CA1 (0.56) LMNASLC6A2HTR2BCA1CA2
Lithium Ion SCHEMBL28825266 0.76 CA1 (0.30) CA1CA2
SCHEMBL25762984 0.75 GPR55 (0.37) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL26562345 0.75
SCHEMBL13326904 0.73 LMNA (0.35) LMNATRPA1CHRM1SLC6A2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20230337520-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230337520-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230117045-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337520-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, LPO, LPL LMNA 145/4885TRPA1 114/4885CHRM1 630/4885
US-20230117045-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, CNKSR1, LOXL1 LMNA 207/4885TRPA1 1242/4885CHRM1 159/4885
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND2 LMNA 763/4885TRPA1 380/4885CHRM1 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.