Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799744 | 0.84 | TSHR (0.39) | TSHRALDH1A1THRBTGFBR1 | |
| SCHEMBL4064266 | 0.81 | ALDH1A1 (0.45) | TSHRALDH1A1THRB | |
| SCHEMBL9504876 | 0.79 | — | — | |
| SCHEMBL4065864 | 0.78 | THRB (0.44) | TSHRALDH1A1THRB | |
| SCHEMBL4275762 | 0.76 | TSHR (0.36) | TSHRALDH1A1THRBTGFBR1AKR1B1 | |
| SCHEMBL4276220 | 0.76 | TSHR (0.36) | TSHRALDH1A1THRBTGFBR1AKR1B1 | |
| SCHEMBL4067172 | 0.75 | THRB (0.39) | TSHRALDH1A1THRB | |
| SCHEMBL35385 | 0.74 | TSHR (0.45) | TSHRALDH1A1THRBTGFBR1 | |
| SCHEMBL7116678 | 0.74 | TSHR (0.45) | TSHRALDH1A1THRBTGFBR1 | |
| SCHEMBL3679800 | 0.74 | TSHR (0.45) | TSHRALDH1A1THRBTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888660-B1 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | CIS PHARMA AG (CH) | 2017-05-17 | — | — | EP | claimed |
| EP-3202369-B1 | INTRAOCULAR LENSES WITH QUANTUM DOTS | CHU MILTON W (US) | 2018-12-05 | — | — | EP | disclosed |
| EP-3202369-A1 | INTRAOCULAR LENSES WITH QUANTUM DOTS | Chu, Milton W. (US) | 2017-08-09 | — | — | EP | disclosed |
| US-9277988-B1 | Intraocular lenses with quantum dots | CHU MILTON W (US) | 2016-03-08 | — | — | US | disclosed |
| EP-2555707-B1 | INTRAOCULAR LENSES WITH HIGH CONTRAST HAPTICS, MATERIALS, AND METHODS | CHU MILTON W (US) | 2015-07-29 | — | — | EP | disclosed |
| EP-2555707-A1 | INTRAOCULAR LENSES WITH HIGH CONTRAST HAPTICS, MATERIALS, AND METHODS | Chu, Milton W. (US) | 2013-02-13 | — | — | EP | disclosed |
| US-8308800-B2 | Intraocular lenses with high contrast haptics, materials, and methods | CHU MILTON W (US) | 2012-11-13 | — | — | US | disclosed |
| WO-2011127079-A1 | INTRAOCULAR LENSES WITH HIGH CONTRAST HAPTICS, MATERIALS, AND METHODS | CHU MILTON W (US) | 2011-10-13 | — | — | WO | disclosed |
| US-20110251685-A1 | Intraocular lenses with high contrast haptics, materials, and methods | CHU MILTON W | 2011-10-13 | — | — | US | disclosed |