Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067172 | 0.87 | THRB (0.39) | THRBTSHRALDH1A1 | |
| SCHEMBL4062183 | 0.84 | TSHR (0.42) | THRBTSHRALDH1A1CYP2C19 | |
| SCHEMBL4064266 | 0.82 | ALDH1A1 (0.45) | THRBTSHRALDH1A1 | |
| SCHEMBL11105602 | 0.82 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL28569358 | 0.78 | THRB (0.50) | THRBTSHRALDH1A1 | |
| SCHEMBL2515977 | 0.78 | TSHR (0.39) | THRBTSHRALDH1A1 | |
| SCHEMBL4065862 | 0.77 | TSHR (0.40) | THRBTSHRALDH1A1 | |
| SCHEMBL3648810 | 0.77 | THRB (0.48) | THRBTSHRALDH1A1 | |
| SCHEMBL28180557 | 0.77 | THRB (0.48) | THRBTSHRALDH1A1 | |
| SCHEMBL11434772 | 0.75 | THRB (0.47) | THRBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158302-A2 | VISCOUS ALPHA-CYANOACRYLATE COMPOSITIONS | CLOSURE MEDICAL CORPORATION (US) | 2009-12-30 | — | — | WO | claimed |
| WO-2009158302-A2 | VISCOUS ALPHA-CYANOACRYLATE COMPOSITIONS | CLOSURE MEDICAL CORPORATION (US) | 2009-12-30 | — | — | WO | disclosed |