Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22849785 | 0.86 | LTA4H (0.38) | KMT2AMEN1SIGMAR1GAAALDH1A1 | |
| SCHEMBL25159854 | 0.78 | MAPT (0.40) | KMT2AMEN1SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22849925 | 0.75 | MAPT (0.48) | KMT2AMEN1 | |
| SCHEMBL22057302 | 0.75 | ADORA1 (0.37) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL22849597 | 0.73 | SIGMAR1 (0.46) | KMT2AMEN1SIGMAR1SMN1; SMN2GAA | |
| SCHEMBL10223324 | 0.71 | ADRB2 (0.64) | KMT2AMEN1SMN1; SMN2POLBKDM4E | |
| SCHEMBL21964548 | 0.71 | SIGMAR1 (0.47) | KMT2AMEN1SIGMAR1ALDH1A1LMNA | |
| SCHEMBL21570189 | 0.71 | MEN1 (0.50) | KMT2AMEN1SIGMAR1SMN1; SMN2GAA | |
| SCHEMBL24158999 | 0.70 | SIGMAR1 (0.47) | KMT2AMEN1SIGMAR1SMN1; SMN2GAA | |
| SCHEMBL13153193 | 0.70 | MEN1 (0.53) | KMT2AMEN1SIGMAR1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230123569-A1 | COMPOUNDS AS AUTOTAXIN INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | LIGACHEM BIOSCIENCES INC. (KR) | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230123569-A1 | COMPOUNDS AS AUTOTAXIN INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | ENPP2, PLA2G10, LPCAT1 | KMT2A 1905/4885MEN1 1247/4885SIGMAR1 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.