SCHEMBL251670

SCHEMBL251670

c1ccc2c(c1)[nH]c1ccc3nccnc3c12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 6/20 0.49
GABRG2 P18507 6/20 0.49
GABRB3 P28472 6/20 0.49
GABRA5 P31644 6/20 0.49
GABRA3 P34903 6/20 0.49
GABRA2 P47869 6/20 0.49
CDK4 P11802 1/20 0.49
CCND1 P24385 1/20 0.49
GABRP O00591 3/20 0.49
GABRD O14764 3/20 0.49
GABRB1 P18505 3/20 0.49
GABRB2 P47870 3/20 0.49
GABRA4 P48169 3/20 0.49
GABRE P78334 3/20 0.49
GABRA6 Q16445 3/20 0.49
GABRG1 Q8N1C3 3/20 0.49
GABRG3 Q99928 3/20 0.49
GABRQ Q9UN88 3/20 0.49
IMPDH2 P12268 1/20 0.46
IMPDH1 P20839 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25679955 0.82 SMN1; SMN2 (0.61) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL29847738 0.82 SMN1; SMN2 (0.61) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL30090463 0.80 LMNA (0.45) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL3817081 0.79 IMPDH2 (0.44) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL28534943 0.79 IMPDH2 (0.44) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL9436889 0.78 GABRA1 (0.47) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL29946446 0.77 CDK4 (0.55) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL542799 0.77 CDK4 (0.55) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL32691812 0.77 TDO2 (0.51) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL2484640 0.77 TDO2 (0.51) GABRA1GABRG2GABRB3GABRA5GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 569 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777140-A Thermal activation delay fluorescent material with double charge transfer channels and aggregation-induced emission characteristics and application thereof 常州大学 2024-03-29 CN claimed
EP-3563185-B1 POLARIZING ARTICLE AND METHOD OF FORMING A POLARIZING ARTICLE TRANSITIONS OPTICAL LTD (IE) 2024-01-31 EP claimed
CN-115991707-A Preparation method of indoloquinoxaline compound 西安凯翔生物医药科技有限公司 2023-04-21 CN claimed
CN-110114703-B Polarized article and method of forming a polarized article 光学转变有限公司 2022-01-11 CN claimed
EP-2969499-B1 METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION TRANSITIONS OPTICAL INC (US) 2021-12-08 EP claimed
US-10884288-B2 Polarizing article and method of forming a polarizing article TRANSITIONS OPTICAL, LTD. (IE) 2021-01-05 US claimed
EP-2969468-B1 METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION TRANSITIONS OPTICAL INC (US) 2020-12-23 EP claimed
US-20200103571-A1 Polarizing Article and Method of Forming a Polarizing Article TRANSITIONS OPTICAL, LTD. (IE) 2020-04-02 US claimed
EP-2895897-B1 A PHOTOCHROMIC ARTICLE HAVING TWO AT LEAST PARTIALLY CROSSED PHOTOCHROMIC-DICHROIC LAYERS TRANSITIONS OPTICAL INC (US) 2020-03-25 EP claimed
CN-105121141-B Method for preparing photochromic-dichroic films with reduced optical distortion 光学转变公司 2019-12-24 CN claimed
US-6472395-B1 Agent for use in transplantation LEIF J. I. LUNDBLAD (SE) 2002-10-29 US claimed
WO-2001060371-A1 USE OF A COMPOUND FOR PREPARING A DRUG LUNDBLAD, LEIF, J., I. (SE) 2001-08-23 WO claimed
EP-0231159-B1 Indoloquinoxalines with substituents in 6-position containing cyclic groups LUNDBLAD LEIF (SE) 1994-08-10 EP claimed
EP-0238459-B1 SUBSTITUTED INDOLOQUINOXALINES Lundblad, Leif (SE) 1992-04-15 EP claimed
US-4990510-A Viricides, anticancer agents LEIF LUNDBLAD (BE) 1991-02-05 US claimed
US-4916124-A Indoloquinoxalines with substituents in 6-position containing cyclic groups as antiviral agents Lundblad, Lief (SE) 1990-04-10 US claimed
EP-0238459-A1 Substituted indoloquinoxalines Lundblad, Leif (SE) 1987-09-23 EP claimed
EP-0231159-A1 Indoloquinoxalines with substituents in 6-position containing cyclic groups Lundblad, Leif (SE) 1987-08-05 EP claimed
WO-1987004436-A1 SUBSTITUTED INDOLOQUINOXALINES LUNDBLAD, LEIF (SE) 1987-07-30 WO claimed
WO-1987004437-A1 INDOLOQUINOXALINES WITH SUBSTITUENTS IN 6-POSITION CONTAINING CYCLIC GROUPS LUNDBLAD, LEIF (SE) 1987-07-30 WO claimed