SCHEMBL2517246

SCHEMBL2517246

OC1C(O)C(O)C(O)(F)C(O)C1O

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
APP P05067 1/20 0.36
IDUA P35475 1/20 0.31
GBA1 P04062 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9795940 1.00 LMNA (0.36) LMNAAPPIDUAGBA1GAA
SCHEMBL2461308 1.00 LMNA (0.36) LMNAAPPIDUAGBA1GAA
SCHEMBL2461938 1.00 LMNA (0.36) LMNAAPPIDUAGBA1GAA
SCHEMBL2461641 1.00 LMNA (0.36) LMNAAPPIDUAGBA1GAA
SCHEMBL12311529 1.00 LMNA (0.36) LMNAAPPIDUAGBA1GAA
SCHEMBL2468220 1.00 LMNA (0.36) LMNAAPPIDUAGBA1GAA
SCHEMBL2517248 1.00 LMNA (0.36) LMNAAPPIDUAGBA1GAA
SCHEMBL9796346 1.00 LMNA (0.36) LMNAAPPIDUAGBA1GAA
SCHEMBL9796369 0.76
SCHEMBL27913293 0.72 LMNA (0.46) LMNAAPPGBA1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110250132-A1 LIPOIC ACID METABOLITE: USEFUL FOR DRUG CARRIER, NANOPARTICLE CONJUGATE, IMAGING AND HYPERTHERMIA THERAPY Seetharama, Ravikumar Kabyadi (US) 2011-10-13 US claimed
US-20110251138-A1 LIPOIC ACID METABOLITE CONJUGATE: PREPARATION AND THEIR THERAPEUTIC EFFECT Seetharama, Ravikuma Kabyadi (US) 2011-10-13 US claimed
US-5998485-A DOSE DEPENDENT CEDARS-SINAI MEDICAL CENTER (US) 1999-12-07 US claimed
WO-1998057620-B1 INOSITOL FOR MODULATION OF IMMUNE RESPONSE CEDARS SINAI MEDICAL CENTER (US) 1999-04-15 WO claimed
WO-1998057620-A2 INOSITOL FOR MODULATION OF IMMUNE RESPONSE CEDARS-SINAI MEDICAL CENTER (US) 1998-12-23 WO claimed
CN-109680035-B Screening method and application of inositol-deficient strain 上海市食品药品检验研究院 2022-11-04 CN disclosed
CN-109680035-A Screening method and application of inositol-deficient strain 上海市食品药品检验所 2019-04-26 CN disclosed
US-20110251138-A1 LIPOIC ACID METABOLITE CONJUGATE: PREPARATION AND THEIR THERAPEUTIC EFFECT Seetharama, Ravikuma Kabyadi (US) 2011-10-13 US disclosed
US-20110250132-A1 LIPOIC ACID METABOLITE: USEFUL FOR DRUG CARRIER, NANOPARTICLE CONJUGATE, IMAGING AND HYPERTHERMIA THERAPY Seetharama, Ravikumar Kabyadi (US) 2011-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110250132-A1 LIPOIC ACID METABOLITE: USEFUL FOR DRUG CARRIER, NANOPARTICLE CONJUGATE, IMAGING AND HYPERTHERMIA THERAPY SLC25A1, LDHA, HOGA1 LMNA 2276/4885APP 3923/4885IDUA 1135/4885
US-20110251138-A1 LIPOIC ACID METABOLITE CONJUGATE: PREPARATION AND THEIR THERAPEUTIC EFFECT SLC7A5, SLC7A1, SLC25A1 LMNA 1701/4885APP 1024/4885IDUA 470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.