Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886489 | 0.83 | DPP4 (0.54) | SRCLMNAHIF1AKDM4ECYP2D6 | |
| SCHEMBL5862033 | 0.83 | DPP4 (0.54) | SRCLMNAHIF1AKDM4ECYP2D6 | |
| SCHEMBL804146 | 0.83 | DPP4 (0.54) | SRCLMNAHIF1AKDM4ECYP2D6 | |
| SCHEMBL7415779 | 0.83 | DPP4 (0.54) | SRCLMNAHIF1AKDM4ECYP2D6 | |
| SCHEMBL16967371 | 0.83 | DPP4 (0.54) | SRCLMNAHIF1AKDM4ECYP2D6 | |
| SCHEMBL4674647 | 0.83 | DPP4 (0.54) | SRCLMNAHIF1AKDM4ECYP2D6 | |
| SCHEMBL804233 | 0.83 | DPP4 (0.54) | SRCLMNAHIF1AKDM4ECYP2D6 | |
| SCHEMBL16967416 | 0.82 | ADRB2 (0.52) | CYP3A4CYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL831692 | 0.82 | ADRB2 (0.52) | CYP3A4CYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL1585460 | 0.82 | ALOX5 (0.47) | CYP1A2CYP2C9MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11648244-B2 | Methods for the treatment of abnormal involuntary movement disorders | AUSPEX PHARMACEUTICALS, INC. (US) | 2023-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11648244-B2 | Methods for the treatment of abnormal involuntary movement disorders | CKMT1A; CKMT1B, GYS1, MUSK | ESR1 4662/4885ESR2 3879/4885PDCD1 3860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.