Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 10/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 9/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.32 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2525099 | 0.96 | CSNK1D (0.37) | CSNK1DCSNK1ECHRM2CHRM4CHRM5 | |
| SCHEMBL2526796 | 0.76 | TGFBR1 (0.53) | THRBTGFBR1MAPK14KDM4ETGFBR2 | |
| SCHEMBL2524961 | 0.76 | PTGS2 (0.44) | THRBTGFBR1MAPK14AR | |
| SCHEMBL2522830 | 0.76 | THRB (0.53) | CSNK1DCSNK1ETHRBTGFBR1MAPK14 | |
| SCHEMBL2524316 | 0.74 | PTGS2 (0.45) | THRBTGFBR1MAPK14KDM4EALDH1A1 | |
| SCHEMBL2522456 | 0.72 | THRB (0.44) | THRBTGFBR1MAPK14KDM4EALDH1A1 | |
| SCHEMBL2526992 | 0.72 | THRB (0.56) | THRBTGFBR1MAPK14KDM4EALDH1A1 | |
| SCHEMBL2524978 | 0.71 | THRB (0.44) | CSNK1DCSNK1ETHRBTGFBR1 | |
| SCHEMBL2522902 | 0.71 | THRB (0.48) | CSNK1DCSNK1ETHRBTGFBR1MAPK14 | |
| SCHEMBL14844868 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947303-B | Bicyclo-pyridyl pyrazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-12-14 | — | — | CN | disclosed |
| EP-2556073-B1 | BICYCLIC PYRIDINYL PYRAZOLES | BAYER IP GMBH (DE) | 2014-07-23 | — | — | EP | disclosed |
| US-8507472-B2 | Bicyclic pyridinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-08-13 | — | — | US | disclosed |
| CN-102947303-A | Bicyclic pyrimidinyl pyrazoles | BAYER CROPSCIENCE AG | 2013-02-27 | — | — | CN | disclosed |
| EP-2556073-A1 | BICYCLIC PYRIMIDINYL PYRAZOLES | Bayer Intellectual Property GmbH (DE) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011124539-A1 | BICYCLIC PYRIMIDINYL PYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2011-10-13 | — | — | WO | disclosed |
| US-20110251178-A1 | Bicyclic Pyridinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251178-A1 | Bicyclic Pyridinylpyrazoles | PLPBP, PNPO, PIR | CSNK1D 3430/4885CSNK1E 3979/4885CHRM2 2000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.