Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BCL6 | P41182 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30421417 | 1.00 | KCNN3 (0.56) | KCNN3HTTMAPTCYP1A2CYP3A4 | |
| SCHEMBL18912248 | 0.74 | HTT (0.54) | KCNN3HTTMAPTCYP1A2CYP2C9 | |
| SCHEMBL25725895 | 0.74 | KCNN3 (0.81) | KCNN3MAPTPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL17055469 | 0.72 | L3MBTL1 (0.56) | KCNN3HTTMAPTBCL6POLB | |
| SCHEMBL25193575 | 0.72 | KCNN3 (1.00) | KCNN3MAPTPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL2554109 | 0.70 | HTT (0.55) | KCNN3HTTMAPTCYP1A2CYP3A4 | |
| SCHEMBL29091967 | 0.69 | PTGS2 (0.51) | — | |
| SCHEMBL30421421 | 0.68 | KCNN3 (0.44) | KCNN3HTTMAPTBCL6NPC1 | |
| SCHEMBL30421533 | 0.68 | KCNN3 (0.43) | KCNN3HTTPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL4138642 | 0.67 | HTT (0.68) | HTTMAPTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159500-A1 | SK CHANNEL POSITIVE ALLOSTERIC MODULATORS | CHAPMAN UNIVERSITY | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159500-A1 | SK CHANNEL POSITIVE ALLOSTERIC MODULATORS | KCNN1, KCNN4, KCNN2 | KCNN3 4/4885HTT 1211/4885MAPT 3044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.