Quercetin

Quercetin

SCHEMBL25190629

COc1cc(O)c(C(=O)C=Cc2ccccc2)c(OC)c1.O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 9/20 0.61
▸ MEN1 O00255 8/20 0.61
▸ MAPT P10636 6/20 0.61
▸ HSD17B10 Q99714 5/20 0.61
▸ CYP3A4 P08684 5/20 0.61
▸ KDM4E B2RXH2 5/20 0.61
▸ RECQL P46063 4/20 0.61
▸ IPMK Q8NFU5 3/20 0.61
▸ IP6K2 Q9UHH9 3/20 0.61
▸ TDP1 Q9NUW8 3/20 0.61
▸ LMNA P02545 2/20 0.61
▸ APP P05067 2/20 0.61
▸ THRB P10828 2/20 0.61
▸ AKR1B1 P15121 2/20 0.61
▸ ELAVL3 Q14576 2/20 0.61
▸ TP53 P04637 3/20 0.61
▸ ATM Q13315 1/20 0.61
▸ CYP1A2 P05177 5/20 0.58
▸ CYP1A1 P04798 4/20 0.58
▸ CYP1B1 Q16678 4/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flavokawain B SCHEMBL25202899 0.89 MAPT (0.60) KMT2AMEN1MAPTHSD17B10CYP3A4
Quercetin SCHEMBL444562 0.84 MEN1 (0.67) KMT2AMEN1MAPTHSD17B10CYP3A4
Quercetin SCHEMBL25221565 0.84 MEN1 (0.67) KMT2AMEN1MAPTHSD17B10CYP3A4
Quercetin SCHEMBL8442487 0.81 MEN1 (0.70) KMT2AMEN1MAPTHSD17B10CYP3A4
Flavokawain B SCHEMBL25195789 0.80 MAPT (0.66) KMT2AMEN1MAPTHSD17B10CYP3A4
Quercetin SCHEMBL27871277 0.79 MEN1 (0.69) KMT2AMEN1MAPTHSD17B10CYP3A4
Curcumin SCHEMBL20291461 0.79 MEN1 (0.68) KMT2AMEN1MAPTHSD17B10CYP3A4
Isorhamnetin SCHEMBL3715283 0.78 MEN1 (0.93) KMT2AMEN1MAPTHSD17B10CYP3A4
Rhamnetin SCHEMBL555118 0.78 MEN1 (1.00) KMT2AMEN1MAPTHSD17B10CYP3A4
Rhamnetin SCHEMBL7164573 0.78 MEN1 (1.00) KMT2AMEN1MAPTHSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 KMT2A 3188/4885MEN1 2457/4885MAPT 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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