SCHEMBL25191667

SCHEMBL25191667

COc1ccc(/C=C/C(=O)c2ccc(O)cc2)cc1COc1ccc(C)cc1[N+](=O)[O-]

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 10/20 0.67
▸ LMNA P02545 10/20 0.67
▸ CYP1A2 P05177 1/20 0.67
▸ CYP2D6 P10635 1/20 0.67
▸ CYP2C9 P11712 1/20 0.67
▸ CYP2C19 P33261 1/20 0.67
▸ MAPT P10636 9/20 0.61
▸ MEN1 O00255 6/20 0.61
▸ KMT2A Q03164 6/20 0.61
▸ NPSR1 Q6W5P4 4/20 0.61
▸ SMN1; SMN2 Q16637 2/20 0.61
▸ KDM4E B2RXH2 2/20 0.61
▸ MAPK1 P28482 1/20 0.61
▸ HTT P42858 1/20 0.61
▸ HPGD P15428 1/20 0.56
▸ THRB P10828 1/20 0.55
▸ CTSL P07711 1/20 0.53
▸ MITF O75030 1/20 0.52
▸ RECQL P46063 1/20 0.52
▸ RAB9A P51151 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25223533 0.94 ALDH1A1 (0.60) ALDH1A1LMNACYP1A2CYP2D6CYP2C9
SCHEMBL25284637 0.94 ALDH1A1 (0.60) ALDH1A1LMNACYP1A2CYP2D6CYP2C9
SCHEMBL25243967 0.90 ALDH1A1 (0.65) ALDH1A1LMNACYP1A2CYP2D6CYP2C9
SCHEMBL25195698 0.88 ALDH1A1 (0.63) ALDH1A1LMNACYP1A2CYP2D6CYP2C9
SCHEMBL25193881 0.86 ALDH1A1 (0.68) ALDH1A1LMNAMAPTMEN1KMT2A
SCHEMBL25202171 0.85 MEN1 (0.67) ALDH1A1LMNAMAPTMEN1KMT2A
SCHEMBL30383487 0.85 MEN1 (0.67) ALDH1A1LMNAMAPTMEN1KMT2A
SCHEMBL25200540 0.85 KMT2A (0.70) ALDH1A1LMNAMAPTMEN1KMT2A
SCHEMBL30384262 0.85 KMT2A (0.70) ALDH1A1LMNAMAPTMEN1KMT2A
SCHEMBL25209839 0.84 MEN1 (0.66) ALDH1A1LMNAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ALDH1A1 3285/4885LMNA 1180/4885CYP1A2 541/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ALDH1A1 3081/4885LMNA 1817/4885CYP1A2 1041/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ALDH1A1 3081/4885LMNA 1817/4885CYP1A2 1041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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