SCHEMBL25200540

SCHEMBL25200540

COc1ccc(/C=C/C(=O)c2ccc(O)cc2)cc1COc1cc(F)ccc1[N+](=O)[O-]

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 8/20 0.70
▸ ALDH1A1 P00352 8/20 0.70
▸ MEN1 O00255 7/20 0.70
▸ LMNA P02545 6/20 0.70
▸ KDM4E B2RXH2 3/20 0.70
▸ MAPT P10636 7/20 0.60
▸ SMN1; SMN2 Q16637 3/20 0.60
▸ THRB P10828 1/20 0.60
▸ NPSR1 Q6W5P4 3/20 0.57
▸ MAPK1 P28482 1/20 0.57
▸ HTT P42858 1/20 0.57
▸ HPGD P15428 1/20 0.52
▸ CXCL12 P48061 1/20 0.51
▸ CTSL P07711 1/20 0.51
▸ SNCA P37840 1/20 0.51
▸ TDP1 Q9NUW8 1/20 0.50
▸ MITF O75030 1/20 0.50
▸ RECQL P46063 1/20 0.50
▸ RAB9A P51151 1/20 0.50
▸ BACE1 P56817 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30384262 1.00 KMT2A (0.70) KMT2AALDH1A1MEN1LMNAKDM4E
SCHEMBL25284637 0.90 ALDH1A1 (0.60) KMT2AALDH1A1MEN1LMNAKDM4E
SCHEMBL25223533 0.90 ALDH1A1 (0.60) KMT2AALDH1A1MEN1LMNAKDM4E
SCHEMBL25243967 0.90 ALDH1A1 (0.65) KMT2AALDH1A1MEN1LMNAKDM4E
SCHEMBL25184962 0.89 CYP19A1 (0.58) KMT2AALDH1A1MEN1LMNAKDM4E
SCHEMBL25201055 0.86 MEN1 (0.79) KMT2AALDH1A1MEN1LMNAKDM4E
SCHEMBL31233118 0.86 MEN1 (0.79) KMT2AALDH1A1MEN1LMNAKDM4E
SCHEMBL25234886 0.86 MEN1 (0.79) KMT2AALDH1A1MEN1LMNAKDM4E
SCHEMBL25191667 0.85 ALDH1A1 (0.67) KMT2AALDH1A1MEN1LMNAKDM4E
SCHEMBL25193881 0.84 ALDH1A1 (0.68) KMT2AALDH1A1MEN1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B KMT2A 2792/4885ALDH1A1 3285/4885MEN1 3367/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 KMT2A 3188/4885ALDH1A1 3081/4885MEN1 2457/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 KMT2A 3188/4885ALDH1A1 3081/4885MEN1 2457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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