SCHEMBL25196296

SCHEMBL25196296

CN(C)S(=O)(=O)c1ccc(C(=O)/C=C/c2ccc(O)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.74
F3 P13726 3/20 0.66
CRHBP P24387 1/20 0.65
CRHR2 Q13324 1/20 0.65
TLR9 Q9NR96 1/20 0.65
MAPT P10636 5/20 0.61
RAB9A P51151 4/20 0.61
MAOB P27338 4/20 0.61
MAOA P21397 2/20 0.61
POLB P06746 1/20 0.61
P4HB P07237 2/20 0.59
BCHE P06276 1/20 0.58
ESR1 P03372 1/20 0.57
ESR2 Q92731 1/20 0.57
CXCL12 P48061 1/20 0.57
KMT2A Q03164 4/20 0.57
MEN1 O00255 3/20 0.57
ALDH1A1 P00352 2/20 0.57
CALM1 P0DP23 1/20 0.57
XDH P47989 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25193155 0.89 LMNA (0.74) LMNAF3CRHBPCRHR2TLR9
SCHEMBL25244774 0.89 LMNA (0.74) LMNAF3CRHBPCRHR2TLR9
SCHEMBL25190857 0.89 LMNA (0.74) LMNAF3CRHBPCRHR2TLR9
SCHEMBL25190877 0.85 MAOB (0.75) LMNAF3CRHBPCRHR2TLR9
SCHEMBL25202389 0.84 P4HB (0.76) LMNAMAPTRAB9AP4HBBCHE
SCHEMBL30383949 0.84 P4HB (0.76) LMNAMAPTRAB9AP4HBBCHE
SCHEMBL30382894 0.84 P4HB (0.76) LMNAMAPTRAB9AP4HBBCHE
SCHEMBL25191096 0.84 P4HB (0.76) LMNAMAPTRAB9AP4HBBCHE
SCHEMBL30383278 0.83 PTGS2 (0.63) LMNAMAPTMAOBPOLBP4HB
SCHEMBL30384088 0.83 PTGS2 (0.63) LMNAMAPTMAOBPOLBP4HB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B LMNA 1180/4885F3 5/4885CRHBP 1697/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 LMNA 1817/4885F3 11/4885CRHBP 1079/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 LMNA 1817/4885F3 11/4885CRHBP 1079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.