Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30401929 | 1.00 | ALDH1A1 (0.32) | ALDH1A1GABRB3NOS3NOS1NOS2 | |
| SCHEMBL25194933 | 0.84 | ALDH1A1 (0.34) | ALDH1A1GABRB3 | |
| SCHEMBL30403137 | 0.72 | CTSK (0.37) | ALDH1A1 | |
| SCHEMBL25188943 | 0.72 | CTSK (0.37) | ALDH1A1 | |
| SCHEMBL26707584 | 0.69 | HMGCR (0.37) | ALDH1A1 | |
| SCHEMBL25191584 | 0.68 | GABRA1 (0.39) | ALDH1A1 | |
| SCHEMBL30402091 | 0.68 | GABRA1 (0.39) | ALDH1A1 | |
| SCHEMBL31128248 | 0.67 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL11917199 | 0.65 | GRM1 (0.36) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL30403001 | 0.64 | SMN1; SMN2 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086801-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023086801-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |