SCHEMBL25212109

SCHEMBL25212109

CC(C)(C)c1c(Br)cc2cc3ccccc3cc2c1C(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.34
▸ HSD17B10 Q99714 2/20 0.34
▸ HIF1A Q16665 1/20 0.34
▸ CYP1B1 Q16678 1/20 0.34
▸ NQO1 P15559 1/20 0.34
▸ CYP2A6 P11509 1/20 0.33
▸ NCEH1 Q6PIU2 1/20 0.33
▸ KDM4E B2RXH2 2/20 0.31
▸ GAA P10253 2/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ HDAC1 Q13547 1/20 0.31
▸ HDAC7 Q8WUI4 1/20 0.31
▸ HDAC8 Q9BY41 1/20 0.31
▸ HDAC6 Q9UBN7 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11377784 0.81 NQO1 (0.36) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
SCHEMBL22411205 0.76 NQO1 (0.33) ALDH1A1HSD17B10HIF1ANQO1CYP2A6
SCHEMBL3420318 0.76 ALDH1A1 (0.40) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
SCHEMBL27686228 0.74 ALDH1A1 (0.39) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
SCHEMBL354096 0.74 ALDH1A1 (0.39) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
SCHEMBL9651812 0.73 CA2 (0.41) ALDH1A1GAAMEN1MAPTKMT2A
SCHEMBL16219583 0.73 ALDH1A1 (0.34) ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6
SCHEMBL5010176 0.72 NQO1 (0.39) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
SCHEMBL25193124 0.71 GPR84 (0.34) ALDH1A1NQO1KDM4EGAAMAPT
SCHEMBL1816984 0.71 ALDH1A1 (0.48) ALDH1A1HSD17B10HIF1ACYP1B1NQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051495-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A SILOCON BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR DOW GLOBAL TECHNOLOGIES LLC (US) 2025-02-13 — — US disclosed
US-20250034292-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A GERMANIUM BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR DOW GLOBAL TECHNOLOGIES LLC (US) 2025-01-30 — — US disclosed
US-20250011478-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A CARBON BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR DOW GLOBAL TECHNOLOGIES LLC (US) 2025-01-09 — — US disclosed
EP-4437012-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A CARBON BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLY ETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR Dow Global Technologies LLC (US) 2024-10-02 — — EP disclosed
EP-4437011-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A GERMANIUM BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR Dow Global Technologies LLC (US) 2024-10-02 — — EP disclosed
EP-4437013-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A SILOCON BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR Dow Global Technologies LLC (US) 2024-10-02 — — EP disclosed
CN-118451111-A Supported catalyst system containing silicon-bridged, anthracenyl-substituted bis-biphenyl-phenoxy organometallic compounds for preparing polyethylene and polyethylene copolymer resins in a gas phase polymerization reactor 陶氏环球技术有限责任公司 2024-08-06 — — CN disclosed
CN-118302456-A Supported catalyst system containing germanium bridged, anthracenyl substituted bis-biphenyl-phenoxy organometallic compounds for preparing polyethylene and polyethylene copolymer resins in a gas phase polymerization reactor 陶氏环球技术有限责任公司 2024-07-05 — — CN disclosed
CN-118302457-A Supported catalyst system containing carbon-bridged, anthracenyl-substituted bis-biphenyl-phenoxy organometallic compounds for preparing polyethylene and polyethylene copolymer resins in a gas phase polymerization reactor 陶氏环球技术有限责任公司 2024-07-05 — — CN disclosed
CN-113597438-B Mono-dentate aminopyridine IV group transition metal olefin copolymerization catalyst with ultra-high molecular weight capability and ultra-low comonomer combination 陶氏环球技术有限责任公司 2024-02-13 — — CN disclosed
WO-2023096865-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A SILOCON BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-01 — — WO disclosed
WO-2023096868-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A GERMANIUM BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-01 — — WO disclosed
WO-2023096864-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A CARBON BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLY ETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-01 — — WO disclosed
CN-113748138-A Biaryl hydroxythiophene group IV transition metal polymerization with chain transfer capability 陶氏环球技术有限责任公司 2021-12-03 — — CN disclosed
CN-113597438-A Mono-tooth aminopyridine group IV transition metal olefin copolymerization catalyst with ultra-high molecular weight capability and ultra-low comonomer combination 陶氏环球技术有限责任公司 2021-11-02 — — CN disclosed
CN-113348186-A Biaryl hydroxy thiophene IV group transition metal polymerization catalyst with chain transfer capability 陶氏环球技术有限责任公司 2021-09-03 — — CN disclosed
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