Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20920037 | 0.81 | GPR119 (0.49) | POLBGPR119 | |
| SCHEMBL20919473 | 0.81 | MGLL (0.36) | LMNASMN1; SMN2MGLLITGB3ITGA2B | |
| SCHEMBL30186325 | 0.74 | GPR119 (0.33) | POLBSMN1; SMN2GPR119 | |
| SCHEMBL30225407 | 0.73 | SMN1; SMN2 (0.54) | OPRD1OPRK1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL21384398 | 0.72 | SMN1; SMN2 (0.52) | OPRD1OPRK1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL30177238 | 0.72 | SMN1; SMN2 (0.52) | OPRD1OPRK1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL30002152 | 0.70 | SMN1; SMN2 (0.50) | OPRD1OPRK1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL30135739 | 0.70 | LMNA (0.50) | OPRD1OPRK1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL29502235 | 0.69 | LMNA (0.49) | OPRD1OPRK1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL30177286 | 0.69 | SMN1; SMN2 (0.49) | OPRD1OPRK1LMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3697781-B1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | UNIV VANDERBILT (US) | 2023-06-07 | — | — | EP | disclosed |