Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30446010 | 0.86 | L3MBTL1 (0.44) | L3MBTL1RAB9AKDM4ELMNAMAPT | |
| SCHEMBL25220100 | 0.84 | L3MBTL1 (0.47) | L3MBTL1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL5329429 | 0.82 | L3MBTL1 (0.66) | L3MBTL1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL14609009 | 0.82 | L3MBTL1 (0.66) | L3MBTL1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL6041724 | 0.76 | LMNA (0.43) | L3MBTL1RAB9AKDM4ELMNAMAPT | |
| SCHEMBL13242436 | 0.75 | CYP3A4 (0.66) | RAB9ALMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL10076388 | 0.75 | CYP3A4 (0.66) | RAB9ALMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL3065638 | 0.75 | RAB9A (0.43) | RAB9AMAPTALDH1A1NPC1SIGMAR1 | |
| SCHEMBL15136612 | 0.75 | RAB9A (0.43) | RAB9AMAPTALDH1A1NPC1SIGMAR1 | |
| SCHEMBL25261092 | 0.74 | KDM4E (0.47) | RAB9AKDM4ELMNAMAPTMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102477-A1 | PERIPHERALLY AND LUMINALLY-RESTRICTED INHIBITORS OF THE SEROTONIN TRANSPORTER AS TREATMENTS FOR DISORDERS OF GASTROINTESTINAL MOTILITY | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-06-08 | — | — | WO | disclosed |