Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25220163 | 0.84 | L3MBTL1 (0.45) | L3MBTL1SLC6A3CYP3A4ALDH1A1TP53 | |
| SCHEMBL30446010 | 0.80 | L3MBTL1 (0.44) | L3MBTL1TP53TACR1RAB9AKDM4E | |
| SCHEMBL30589885 | 0.80 | L3MBTL1 (0.70) | L3MBTL1SLC6A3CYP3A4ALDH1A1TP53 | |
| SCHEMBL19236199 | 0.80 | L3MBTL1 (0.70) | L3MBTL1SLC6A3CYP3A4ALDH1A1TP53 | |
| SCHEMBL7957720 | 0.80 | L3MBTL1 (0.70) | L3MBTL1SLC6A3CYP3A4ALDH1A1TP53 | |
| SCHEMBL9526894 | 0.80 | L3MBTL1 (0.70) | L3MBTL1SLC6A3CYP3A4ALDH1A1TP53 | |
| Iodide SCHEMBL25220873 | 0.79 | CYP3A4 (0.43) | L3MBTL1SLC6A3CYP3A4ALDH1A1TP53 | |
| SCHEMBL10076388 | 0.78 | CYP3A4 (0.66) | SLC6A3CYP3A4ALDH1A1TP53CYP1A2 | |
| SCHEMBL13242436 | 0.78 | CYP3A4 (0.66) | SLC6A3CYP3A4ALDH1A1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL25272655 | 0.77 | CYP3A4 (0.66) | SLC6A3CYP3A4ALDH1A1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250042855-A1 | PERIPHERALLY AND LUMINALLY-RESTRICTED INHIBITORS OF THE SEROTONIN TRANSPORTER AS TREATMENTS FOR DISORDERS OF GASTROINTESTINAL MOTILITY AND GUT-BRAIN AXIS | THE JOHNS HOPKINS UNIVERSITY | 2025-02-06 | — | — | US | disclosed |
| WO-2023102477-A1 | PERIPHERALLY AND LUMINALLY-RESTRICTED INHIBITORS OF THE SEROTONIN TRANSPORTER AS TREATMENTS FOR DISORDERS OF GASTROINTESTINAL MOTILITY | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250042855-A1 | PERIPHERALLY AND LUMINALLY-RESTRICTED INHIBITORS OF THE SEROTONIN TRANSPORTER AS TREATMENTS FOR DISORDERS OF GASTROINTESTINAL MOTILITY AND GUT-BRAIN AXIS | SLC6A4, HTR6, HTR5A | L3MBTL1 2949/4885SLC6A3 84/4885CYP3A4 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.