Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | SI | P14410 | 4/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25270762 | 0.92 | ALDH1A1 (0.51) | MGAMGAASIMGAM2NPSR1 | |
| SCHEMBL25223726 | 0.83 | CNR1 (0.40) | ALDH1A1LMNAHTTMAPTNOD2 | |
| SCHEMBL25271592 | 0.81 | ABL1 (0.42) | GAAALDH1A1MAPTNOD2BACE1 | |
| SCHEMBL13251065 | 0.79 | ACACA (0.59) | NPSR1ALDH1A1LMNAHTTMAPT | |
| SCHEMBL28691479 | 0.78 | CYP19A1 (0.43) | MGAMGAASIMGAM2NPSR1 | |
| SCHEMBL13251023 | 0.76 | ABL1 (0.52) | GAAALDH1A1MAPK1NOD2MAOB | |
| SCHEMBL13251008 | 0.74 | ACACA (0.54) | ALDH1A1HTTMAPTMAPK1BACE1 | |
| SCHEMBL13251118 | 0.74 | ACACA (0.54) | ALDH1A1HTTMAPTMAPK1BACE1 | |
| SCHEMBL25271741 | 0.74 | GAA (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL25224619 | 0.73 | KDM4E (0.43) | GAANPSR1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023103611-A1 | BROMOPYRENE INTERMEDIATE AND DERIVATIVES THEREOF, PREPARATION METHOD, AND USE | 广东工业大学 | 2023-06-15 | — | — | WO | disclosed |
| WO-2023103611-A1 | BROMOPYRENE INTERMEDIATE AND DERIVATIVES THEREOF, PREPARATION METHOD, AND USE | 广东工业大学 | 2023-06-15 | — | — | WO | disclosed |
| CN-114149307-B | Bromopyrene intermediate and derivative, preparation method and application thereof | 广东工业大学 | 2023-04-11 | — | — | CN | disclosed |
| CN-114149307-A | Bromopyrene intermediate and derivative, preparation method and application thereof | 广东工业大学 | 2022-03-08 | — | — | CN | disclosed |