SCHEMBL25224147

SCHEMBL25224147

CC(C)CC(C)Nc1ccc(Nc2ccccc2C(C)(C)O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
CYP3A4 P08684 4/20 0.60
ALOX15 P16050 3/20 0.60
TSHR P16473 3/20 0.60
HSD17B10 Q99714 3/20 0.60
ALOX12 P18054 2/20 0.60
HIF1A Q16665 2/20 0.60
MAPK1 P28482 1/20 0.60
TDP1 Q9NUW8 4/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
THRB P10828 2/20 0.37
LMNA P02545 2/20 0.37
RECQL P46063 2/20 0.37
ATM Q13315 1/20 0.37
PLK1 P53350 2/20 0.36
TP53 P04637 1/20 0.36
HSP90AA1 P07900 1/20 0.36
CASP1 P29466 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KCNH3 Q9ULD8 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16962432 0.81 ALDH1A1 (0.66) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL12109310 0.78 PTGER4 (0.39) ALDH1A1CYP3A4ALOX15HSD17B10ALOX12
SCHEMBL31916 0.78 MAPT (0.47) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL39447 0.76 ALDH1A1 (1.00) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL31215174 0.76 ALDH1A1 (1.00) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL15476044 0.76 ALDH1A1 (1.00) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL24914673 0.76 ALDH1A1 (0.63) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL9933293 0.76 ALDH1A1 (0.85) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL16962232 0.75 ALDH1A1 (0.58) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL10828908 0.75 ALDH1A1 (0.67) ALDH1A1CYP3A4ALOX15TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4441136-B1 COMPOUND, RUBBER BLEND CONTAINING THE COMPOUND, VEHICLE TIRE COMPRISING THE RUBBER BLEND IN AT LEAST ONE COMPONENT, PROCESS FOR PRODUCING THE COMPOUND, AND USE OF THE COMPOUND AS AN AGEING PROTECTANT AND/OR ANTIOXIDANT AND/OR DYE CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2025-11-26 EP disclosed
US-20250109108-A1 COMPOUND, RUBBER BLEND CONTAINING THE COMPOUND, VEHICLE TIRE COMPRISING THE RUBBER BLEND IN AT LEAST ONE COMPONENT, PROCESS FOR PRODUCING THE COMPOUND, AND USE OF THE COMPOUND AS AN AGEING PROTECTANT AND/OR ANTIOXIDANT AND/OR DYE CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2025-04-03 US disclosed
WO-2023098953-A1 COMPOUND, RUBBER BLEND CONTAINING THE COMPOUND, VEHICLE TIRE COMPRISING THE RUBBER BLEND IN AT LEAST ONE COMPONENT, PROCESS FOR PRODUCING THE COMPOUND, AND USE OF THE COMPOUND AS AN AGEING PROTECTANT AND/OR ANTIOXIDANT AND/OR DYE CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2023-06-08 WO disclosed
WO-2023098953-A1 COMPOUND, RUBBER BLEND CONTAINING THE COMPOUND, VEHICLE TIRE COMPRISING THE RUBBER BLEND IN AT LEAST ONE COMPONENT, PROCESS FOR PRODUCING THE COMPOUND, AND USE OF THE COMPOUND AS AN AGEING PROTECTANT AND/OR ANTIOXIDANT AND/OR DYE CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2023-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250109108-A1 COMPOUND, RUBBER BLEND CONTAINING THE COMPOUND, VEHICLE TIRE COMPRISING THE RUBBER BLEND IN AT LEAST ONE COMPONENT, PROCESS FOR PRODUCING THE COMPOUND, AND USE OF THE COMPOUND AS AN AGEING PROTECTANT AND/OR ANTIOXIDANT AND/OR DYE POT1, TERT, KEAP1 ALDH1A1 1223/4885CYP3A4 204/4885ALOX15 459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.