SCHEMBL31916

SCHEMBL31916

CC(C)(O)c1ccccc1Nc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
GAA P10253 4/20 0.47
TDP1 Q9NUW8 4/20 0.47
KDM4E B2RXH2 2/20 0.47
RECQL P46063 2/20 0.47
GLA P06280 1/20 0.47
ALDH1A1 P00352 6/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2D6 P10635 2/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
LMNA P02545 2/20 0.45
ALOX15 P16050 4/20 0.44
FABP4 P15090 2/20 0.43
HSD17B10 Q99714 4/20 0.42
HPGD P15428 4/20 0.42
TSHR P16473 3/20 0.42
CYP3A4 P08684 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12109310 0.89 PTGER4 (0.39) MAPTMEN1KMT2AGAATDP1
SCHEMBL796967 0.85 MEN1 (0.39) MAPTMEN1KMT2AGAATDP1
SCHEMBL17617068 0.85 MEN1 (0.41) MAPTMEN1KMT2AGAATDP1
SCHEMBL24268313 0.85 SIRT2 (0.52) MAPTMEN1KMT2AGAATDP1
SCHEMBL11202038 0.83 MAPT (0.50) MAPTMEN1KMT2AGAATDP1
SCHEMBL8962199 0.83 TDP1 (0.50) MAPTMEN1KMT2AGAATDP1
SCHEMBL13231954 0.83 MAPT (0.42) MAPTMEN1KMT2AGAATDP1
SCHEMBL13286497 0.81 CXCR2 (0.41) MAPTMEN1KMT2AGAATDP1
SCHEMBL1302379 0.81 ACP1 (0.40) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL19626178 0.80 CXCR2 (0.47) MAPTMEN1KMT2AGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110240565-B Preparation method of 9, 9-dimethylacridine 郑州原理生物科技有限公司 2021-01-01 CN claimed
US-20230115435-A1 Novel Compound and Organic Light Emitting Device Comprising the Same LG CHEM, LTD. (KR) 2023-04-13 US disclosed
WO-2022045583-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2022-03-03 WO disclosed
US-20210167304-A1 NEW EMITTER MATERIALS AND MATRIX MATERIALS FOR OPTOELECTRONIC AND ELECTRONIC COMPONENTS, IN PARTICULAR ORGANIC LIGHT-EMITTING DIODES (OLEDS) Technische Universität Dresden (DE) 2021-06-03 US disclosed
CN-110240565-B Preparation method of 9, 9-dimethylacridine 郑州原理生物科技有限公司 2021-01-01 CN disclosed
US-10825992-B2 Spirobifluorene compounds for light emitting devices SUMITOMO CHEMICAL CO., LTD (JP) 2020-11-03 US disclosed
US-10700290-B2 Organic compound, and organic light-emitting diode and organic light-emitting diode display device including the same LG DISPLAY CO., LTD. (KR) 2020-06-30 US disclosed
US-20200203630-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2020-06-25 US disclosed
US-10651399-B2 Delayed fluorescence compound, and organic light emitting diode and display device using the same LG DISPLAY CO., LTD. (KR) 2020-05-12 US disclosed
US-10559763-B2 Photoelectric conversion element, imaging device, optical sensor, and method of using photoelectric conversion element FUJIFILM CORPORATION (JP) 2020-02-11 US disclosed
US-20140070146-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2014-03-13 US disclosed
US-20140070146-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2014-03-13 US disclosed
WO-2013045410-A1 SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES SOLVAY SA (BE) 2013-04-04 WO disclosed
WO-2013045411-A1 SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES SOLVAY SA (BE) 2013-04-04 WO disclosed
WO-2012026780-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2012-03-01 WO disclosed
WO-2011093609-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-08-04 WO disclosed
US-20100171417-A1 CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-20100171417-A1 CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-6235730-B1 ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT JAPAN TOBACCO, INC. (JP) 2001-05-22 US disclosed
EP-0970954-A1 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME JAPAN TOBACCO INC. (JP) 2000-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100171417-A1 CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, SLC67A1, SLC26A3 MAPT 3069/4885MEN1 709/4885KMT2A 2827/4885
US-10825992-B2 Spirobifluorene compounds for light emitting devices CRY1, TRPA1, ALDH1A2 MAPT 1628/4885MEN1 2284/4885KMT2A 4286/4885
US-10651399-B2 Delayed fluorescence compound, and organic light emitting diode and display device using the same OCIAD1, OCIAD2, DRD2 MAPT 304/4885MEN1 4465/4885KMT2A 1932/4885
US-10559763-B2 Photoelectric conversion element, imaging device, optical sensor, and method of using photoelectric conversion element PPOX, PIN4, CRY1 MAPT 1641/4885MEN1 618/4885KMT2A 3448/4885
US-10700290-B2 Organic compound, and organic light-emitting diode and organic light-emitting diode display device including the same OCIAD1, OCIAD2, AOX1 MAPT 193/4885MEN1 3145/4885KMT2A 2043/4885
US-20230115435-A1 Novel Compound and Organic Light Emitting Device Comprising the Same NR2E3, ARL1, AR MAPT 1896/4885MEN1 1226/4885KMT2A 2005/4885
US-20210167304-A1 NEW EMITTER MATERIALS AND MATRIX MATERIALS FOR OPTOELECTRONIC AND ELECTRONIC COMPONENTS, IN PARTICULAR ORGANIC LIGHT-EMITTING DIODES (OLEDS) OCIAD2, OCIAD1, OSTC MAPT 65/4885MEN1 4392/4885KMT2A 4292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.