Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30488091 | 0.84 | ADRB1 (0.50) | LMNAADRB1ADRB3ADRB2KMT2A | |
| SCHEMBL25271186 | 0.84 | ADRB1 (0.50) | LMNAADRB1ADRB3ADRB2KMT2A | |
| SCHEMBL7278068 | 0.84 | LMNA (0.77) | LMNAADRB2KDM4EL3MBTL1SLC16A3 | |
| SCHEMBL1849603 | 0.84 | LMNA (0.77) | LMNAADRB2KDM4EL3MBTL1SLC16A3 | |
| SCHEMBL2289990 | 0.84 | LMNA (0.77) | LMNAADRB2KDM4EL3MBTL1SLC16A3 | |
| SCHEMBL10589633 | 0.80 | SMN1; SMN2 (0.61) | LMNAADRB1ADRB3ADRB2KDM4E | |
| SCHEMBL11602525 | 0.77 | ADRB1 (0.49) | LMNAADRB1ADRB3KDM4EL3MBTL1 | |
| SCHEMBL23367359 | 0.77 | SMN1; SMN2 (0.52) | LMNAADRB1ADRB3ADRB2L3MBTL1 | |
| SCHEMBL25229181 | 0.77 | ADRB1 (0.57) | ADRB1ADRB3ADRB2 | |
| SCHEMBL4053207 | 0.77 | ADRB1 (0.57) | ADRB1ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107630-A2 | AMINO ALCOHOL COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107630-A2 | AMINO ALCOHOL COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |