Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SI | P14410 | 3/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25270762 | 0.82 | ALDH1A1 (0.51) | CYP19A1GSK3BCDK5CDK5R1MGAM | |
| SCHEMBL25225360 | 0.78 | MGAM (0.49) | CYP19A1GSK3BCDK5CDK5R1MGAM | |
| SCHEMBL28713191 | 0.74 | ADORA3 (0.37) | ALOX5GAAALDH1A1LMNAHTT | |
| SCHEMBL28935252 | 0.72 | ABCG2 (0.41) | ALOX5GAAALDH1A1MAPT | |
| SCHEMBL6087375 | 0.70 | NPSR1 (0.58) | ALOX5MGAMGAASIMGAM2 | |
| SCHEMBL25436806 | 0.69 | MEN1 (0.43) | BACE1MAOBALDH1A1LMNAMAPT | |
| SCHEMBL21582171 | 0.69 | ALOX5 (0.56) | ALOX5GAAMAOBALDH1A1MAPT | |
| SCHEMBL29409810 | 0.68 | ALOX5 (0.55) | ALOX5MAOB | |
| SCHEMBL6086702 | 0.68 | MGAM (0.56) | ALOX5MGAMGAASIMGAM2 | |
| SCHEMBL8084895 | 0.67 | MAOB (0.53) | CYP19A1ALOX5MAOBNPSR1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149307-A | Bromopyrene intermediate and derivative, preparation method and application thereof | 广东工业大学 | 2022-03-08 | — | — | CN | disclosed |