Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135145 | 0.81 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1GAAKDM4ELMNA | |
| SCHEMBL22708300 | 0.76 | NOS2 (0.33) | — | |
| SCHEMBL22284505 | 0.76 | PKM (0.48) | L3MBTL1ALDH1A1GAAKDM4ELMNA | |
| SCHEMBL28626528 | 0.76 | PKM (0.48) | L3MBTL1ALDH1A1GAAKDM4ELMNA | |
| SCHEMBL22284683 | 0.74 | APP (0.30) | MAPTAPP | |
| SCHEMBL22284512 | 0.72 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1GAAKDM4ECCNC | |
| SCHEMBL22298846 | 0.71 | FBP1 (0.40) | ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL16468579 | 0.68 | RPA1 (0.40) | L3MBTL1ALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL1124471 | 0.68 | HDAC1 (0.54) | L3MBTL1ALDH1A1GAAKDM4ELMNA | |
| SCHEMBL1358017 | 0.68 | HDAC1 (0.54) | L3MBTL1ALDH1A1GAAKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11680057-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11680057-B2 | Pyrazole derivatives | RB1, NQO2, RBX1 | L3MBTL1 4093/4885ALDH1A1 1492/4885GAA 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.