Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25991641 | 0.72 | TAS2R14 (0.39) | TAS2R14KDM4ELMNAHSP90AA1HSP90AB1 | |
| SCHEMBL21614639 | 0.70 | HSP90AA1 (0.40) | TAS2R14KDM4ELMNAHSP90AA1HSP90AB1 | |
| SCHEMBL20399842 | 0.70 | KDM4E (0.41) | TAS2R14KDM4ELMNAHSP90AA1HSP90AB1 | |
| SCHEMBL602851 | 0.70 | ALDH1A1 (0.37) | TAS2R14KDM4ELMNAHSP90AA1HSP90AB1 | |
| SCHEMBL601855 | 0.70 | CYP2C19 (0.40) | TAS2R14KDM4ELMNAHSP90AA1HSP90AB1 | |
| SCHEMBL29976642 | 0.68 | KDM4E (0.63) | KDM4ELMNA | |
| SCHEMBL19805666 | 0.68 | KDM4E (0.63) | KDM4ELMNA | |
| SCHEMBL24027397 | 0.68 | CTSS (0.36) | TAS2R14KDM4ELMNAHSP90AA1HSP90AB1 | |
| SCHEMBL3101735 | 0.67 | NT5E (0.38) | TAS2R14KDM4ELMNAHSP90AA1HSP90AB1 | |
| SCHEMBL23580667 | 0.67 | HSP90AA1 (0.40) | TAS2R14KDM4ELMNAHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130070-A2 | CARBOLINE COMPOUNDS AND USE THEREOF | PTC THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |