Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.34 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.34 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2523832 | 1.00 | SIGMAR1 (0.39) | SIGMAR1HDAC9KIF11SLC6A4SLC6A3 | |
| SCHEMBL1404036 | 0.83 | MITF (0.39) | HDAC9KIF11SLC6A4KMT2A | |
| SCHEMBL6073260 | 0.83 | MITF (0.39) | HDAC9KIF11SLC6A4KMT2A | |
| SCHEMBL15355348 | 0.70 | MEN1 (0.39) | HDAC9KMT2A | |
| SCHEMBL15355355 | 0.70 | ALDH1A1 (0.43) | HDAC9KMT2A | |
| SCHEMBL28703383 | 0.70 | SIGMAR1 (0.39) | SIGMAR1KMT2A | |
| SCHEMBL15355309 | 0.68 | ALDH1A1 (0.38) | HDAC9KMT2A | |
| SCHEMBL22776858 | 0.68 | CHRM5 (0.34) | SIGMAR1HDAC9KMT2A | |
| SCHEMBL2791470 | 0.67 | RAB9A (0.43) | SIGMAR1HDAC9KIF11KMT2AOPRL1 | |
| SCHEMBL9570551 | 0.66 | SIGMAR1 (0.43) | SIGMAR1HDAC9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029587-B1 | PROCESS FOR THE PREPARATION OF SOLIFENACIN | ZENTIVA AS (CZ) | 2015-09-02 | — | — | EP | disclosed |
| US-8034942-B2 | Process for the preparation of solifenacin | Zentiva k s. (CZ) | 2011-10-11 | — | — | US | disclosed |
| US-20090203914-A1 | PROCESS FOR THE PREPARATION OF SOLIFENACIN | ZENTIVA K.S. (CZ) | 2009-08-13 | — | — | US | disclosed |
| EP-2046751-A2 | PROCESS FOR PREPARING SOLIFENACIN AND ITS SALTS | Dr. Reddy's Laboratories Ltd. (IN) | 2009-04-15 | — | — | EP | disclosed |
| EP-2029587-A2 | PROCESS FOR THE PREPARATION OF SOLIFENACIN | Zentiva, A.S. (CZ) | 2009-03-04 | — | — | EP | disclosed |
| WO-2008011462-A2 | PROCESS FOR PREPARING SOLIFENACIN AND ITS SALTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2008-01-24 | — | — | WO | disclosed |
| WO-2007147374-A2 | PROCESS FOR THE PREPARATION OF SOLIFENACIN | ZENTIVA A.S. (CZ) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203914-A1 | PROCESS FOR THE PREPARATION OF SOLIFENACIN | OPRL1, CHRNG, CHRM1 | SIGMAR1 14/4885HDAC9 3895/4885KIF11 3066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.