Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404036 | 1.00 | MITF (0.39) | MITFMEN1KMT2AHDAC9KIF11 | |
| SCHEMBL2523832 | 0.83 | SIGMAR1 (0.39) | KMT2AHDAC9KIF11SLC6A4 | |
| SCHEMBL2525394 | 0.83 | SIGMAR1 (0.39) | KMT2AHDAC9KIF11SLC6A4 | |
| SCHEMBL28703383 | 0.78 | SIGMAR1 (0.39) | MEN1KMT2A | |
| SCHEMBL15355355 | 0.76 | ALDH1A1 (0.43) | MEN1KMT2AHDAC9 | |
| SCHEMBL9375293 | 0.75 | SIGMAR1 (0.46) | MEN1KMT2A | |
| SCHEMBL15355309 | 0.74 | ALDH1A1 (0.38) | MEN1KMT2AHDAC9 | |
| SCHEMBL15355348 | 0.73 | MEN1 (0.39) | MEN1KMT2AHDAC9POLB | |
| SCHEMBL1724164 | 0.71 | SIGMAR1 (0.38) | KIF11OPRM1OPRD1OPRK1 | |
| SCHEMBL22776858 | 0.70 | CHRM5 (0.34) | MEN1KMT2AHDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2484681-A1 | Chemically and chirally pure gentisate salt of solifenacin | Cadila Healthcare Limited (IN) | 2012-08-08 | — | — | EP | disclosed |
| WO-2006035280-A1 | 3,4-DIHYDROISOQUINOLINE COMPOUNDS AS MUSCRINIC RECEPTOR ANTAGONISTS FOR THE TREATMENT OF RESPIRATORY, URINARY AND GASTROINTESTINAL DISEASES | RANBAXY LABORATORIES LIMITED (IN) | 2006-04-06 | — | — | WO | disclosed |