Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528609 | 0.91 | L3MBTL1 (0.40) | L3MBTL1TDP1KMT2AMEN1KDM4E | |
| SCHEMBL2527801 | 0.85 | MEN1 (0.42) | TDP1KMT2AMEN1KDM4EGAA | |
| SCHEMBL2532004 | 0.85 | HSD17B10 (0.44) | L3MBTL1TDP1KMT2AMEN1KDM4E | |
| SCHEMBL2528091 | 0.84 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL2529789 | 0.83 | VNN1 (0.41) | L3MBTL1TDP1KDM4EGAASMN1; SMN2 | |
| SCHEMBL2532055 | 0.82 | CA2 (0.40) | L3MBTL1TDP1KDM4EGAASMN1; SMN2 | |
| SCHEMBL2525469 | 0.82 | GPR119 (0.41) | L3MBTL1TDP1KDM4EGAASMN1; SMN2 | |
| SCHEMBL2531030 | 0.82 | ADRB3 (0.38) | L3MBTL1TDP1KDM4EGAASMN1; SMN2 | |
| SCHEMBL2525562 | 0.82 | MEN1 (0.40) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL2527546 | 0.81 | TDP1 (0.47) | L3MBTL1TDP1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | L3MBTL1 4486/4885TDP1 3871/4885KMT2A 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.