Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25303265 | 0.76 | RXFP1 (0.46) | KMT2AMEN1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL30404969 | 0.76 | RXFP1 (0.46) | KMT2AMEN1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL24110227 | 0.76 | HTR2A (0.38) | KDM4E | |
| SCHEMBL25257851 | 0.74 | DUT (0.45) | KMT2AMEN1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL24110215 | 0.70 | HTR2A (0.42) | KDM4E | |
| SCHEMBL7765161 | 0.68 | ALDH1A1 (0.55) | TDP1KMT2AMEN1RAB9ATSHR | |
| SCHEMBL24110240 | 0.68 | HTR2C (0.38) | — | |
| SCHEMBL25818087 | 0.67 | NR3C1 (0.35) | KDM4E | |
| SCHEMBL13500312 | 0.67 | PARG (0.56) | TDP1KMT2AMEN1RAB9ATSHR | |
| SCHEMBL10282879 | 0.66 | ALDH1A1 (0.56) | KMT2AMEN1RAB9AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507625-A | Isochromic amine nerve plasticizer and application thereof | 德力克斯疗法有限公司 | 2023-07-28 | — | — | CN | disclosed |
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| EP-4165049-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | Delix Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | GAP43, SLC18A2, PNMT | TDP1 393/4885KMT2A 1200/4885MEN1 3118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.