Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.54 |
| ▸ | PTGES | O14684 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.50 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | CBS | P35520 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25302418 | 0.91 | PTGES (0.58) | ALOX5PTGESPPARGCYP3A4CYP2C9 | |
| SCHEMBL25301706 | 0.88 | ALDH1A1 (0.56) | ALOX5PTGESPPARGCYP3A4CYP2C9 | |
| SCHEMBL25256792 | 0.86 | CYP3A4 (0.56) | ALOX5PTGESPPARGCYP3A4CYP2C9 | |
| SCHEMBL19437149 | 0.85 | CYP3A4 (0.68) | ALOX5PTGESPPARGCYP3A4CYP2C9 | |
| SCHEMBL19437161 | 0.85 | CYP3A4 (0.68) | ALOX5PTGESPPARGCYP3A4CYP2C9 | |
| SCHEMBL584959 | 0.85 | CYP3A4 (0.68) | ALOX5PTGESPPARGCYP3A4CYP2C9 | |
| SCHEMBL25257221 | 0.83 | ALOX5 (0.65) | ALOX5PTGESPPARGCYP3A4CYP2C9 | |
| SCHEMBL25254374 | 0.82 | ALOX5 (0.62) | ALOX5PTGESPPARGCYP3A4CYP2C9 | |
| SCHEMBL15263105 | 0.82 | ALOX15 (0.52) | ALOX5CYP3A4CYP2C9GAAMAPT | |
| SCHEMBL1893128 | 0.82 | ALOX15 (0.52) | ALOX5CYP3A4CYP2C9GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | claimed |