Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 10/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12117110 | 0.83 | L3MBTL1 (0.67) | LTA4HFFAR1LMNAL3MBTL1 | |
| SCHEMBL31448501 | 0.82 | PPARA (0.65) | FFAR1LMNAL3MBTL1PPARA | |
| SCHEMBL20799670 | 0.81 | FFAR1 (0.65) | FFAR1LMNAL3MBTL1PPARG | |
| SCHEMBL2891962 | 0.80 | FFAR1 (0.58) | LTA4HFFAR1LMNAL3MBTL1PPARA | |
| SCHEMBL10728695 | 0.80 | PLA2G4B (0.59) | LTA4HFFAR1LMNAL3MBTL1PPARA | |
| SCHEMBL10207287 | 0.78 | LMNA (0.63) | FFAR1LMNAL3MBTL1PPARA | |
| SCHEMBL12099337 | 0.78 | PPARA (0.56) | FFAR1LMNAL3MBTL1PPARA | |
| SCHEMBL31448470 | 0.77 | PPARA (0.73) | FFAR1LMNAL3MBTL1PPARA | |
| SCHEMBL928209 | 0.76 | L3MBTL1 (0.62) | LTA4HFFAR1LMNAL3MBTL1PPARA | |
| SCHEMBL29089242 | 0.75 | PLA2G4B (0.68) | LMNAL3MBTL1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034900-B2 | Water-soluble thioester and selenoester compounds and methods for making and using the same | AMYLIN PHARMACEUTICALS, INC. (US) | 2011-10-11 | — | — | US | disclosed |
| EP-1631597-A4 | DISPLACEABLE LINKER SOLID PHASE CHEMICAL LIGATION | GRYPHON THERAPEUTICS INC (US) | 2007-07-11 | — | — | EP | disclosed |
| US-20060275768-A1 | Multiplex polymer ligation | AMYLIN PHARMACEUTICALS, INC. | 2006-12-07 | — | — | US | disclosed |
| EP-1616021-A4 | MULTIPLEX POLYMER LIGATION | GRYPHON THERAPEUTICS INC (US) | 2006-08-30 | — | — | EP | disclosed |
| US-20060173159-A1 | Water-soluble thioester and selenoester compounds and methods for making and using the same | ASTRAZENECA PHARMACEUTICALS LP | 2006-08-03 | — | — | US | disclosed |
| EP-1631597-A2 | DISPLACEABLE LINKER SOLID PHASE CHEMICAL LIGATION | Gryphon Therapeutics, Inc. (US) | 2006-03-08 | — | — | EP | disclosed |
| EP-1616021-A2 | MULTIPLEX POLYMER LIGATION | Gryphon Therapeutics, Inc. (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004105685-A2 | DISPLACEABLE LINKER SOLID PHASE CHEMICAL LIGATION | GRYPHON THERAPEUTICS, INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| WO-2004060925-A2 | MULTIPLEX POLYMER LIGATION | GRYPHON THERAPEUTICS, INC. (US) | 2004-07-22 | — | — | WO | disclosed |
| WO-2004060863-A2 | BACKBONE ANCHORED THIOESTER AND SELENOESTER GENERATORS | GRYPHON THERAPEUTICS, INC. (US) | 2004-07-22 | — | — | WO | disclosed |
| US-20040132966-A1 | Backbone anchored thioester and selenoester generators | GRYPHON THERAPEUTICS, INC. | 2004-07-08 | — | — | US | disclosed |
| US-20040063902-A1 | Side chain anchored thioester and selenoester generators | GRYPHON THERAPEUTICS, INC. | 2004-04-01 | — | — | US | disclosed |
| WO-2004011424-A2 | SIDE CHAIN ANCHORED THIOESTER AND SELENOESTER GENERATORS | GRYPHON THERAPEUTICS, INC. (US) | 2004-02-05 | — | — | WO | disclosed |
| US-6566494-B1 | Solid support for use in the generation of preferential peptides | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2003-05-20 | — | — | US | disclosed |
| US-5917015-A | Support material for solid phase organic synthesis | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1999-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132966-A1 | Backbone anchored thioester and selenoester generators | SCLY, SELENOI, ETF1 | LTA4H 2674/4885FFAR1 2845/4885LMNA 4373/4885 |
| US-20060173159-A1 | Water-soluble thioester and selenoester compounds and methods for making and using the same | SCLY, TST, SELENOI | LTA4H 2148/4885FFAR1 3591/4885LMNA 3396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.