Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25308135 | 0.86 | KMT2A (0.69) | ABCG2ABCB1KMT2AMEN1RAB9A | |
| SCHEMBL30663838 | 0.86 | KMT2A (0.69) | ABCG2ABCB1KMT2AMEN1RAB9A | |
| SCHEMBL25307372 | 0.84 | ABCG2 (0.67) | ABCG2ABCB1KMT2AMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL25306301 | 0.79 | ABCG2 (0.63) | ABCG2ABCB1ACHEMAPTNAMPT | |
| SCHEMBL5277697 | 0.78 | ABCG2 (0.62) | ABCG2ABCB1ACHEMAPTHTT | |
| SCHEMBL25260710 | 0.78 | POLH (0.72) | ABCB1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL5277304 | 0.76 | ABCG2 (0.59) | ABCG2ABCB1ACHEMAPTHTT | |
| SCHEMBL7896281 | 0.74 | ALDH1A1 (0.57) | ABCG2ABCB1KMT2AMEN1RAB9A | |
| SCHEMBL4972062 | 0.73 | KMT2A (0.81) | ABCB1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL30506423 | 0.72 | ALDH1A1 (0.58) | ABCG2ABCB1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215522-A1 | DERIVATIVES OF 4-CHROMONE AS INHIBITORS OF THE RDRP POLYMERASE OF SARS-COV-2 VIRUS AND METHOD FOR THE PREPARATION THEREOF | Fondazione Istituto Italiano di Tecnologia (IT) | 2023-07-26 | — | — | EP | disclosed |