Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5277304 | 0.88 | ABCG2 (0.59) | ABCG2ABCB1ACHEHTTMAPT | |
| Hydrochloric Acid SCHEMBL25306301 | 0.87 | ABCG2 (0.63) | ABCG2ABCB1ACHEHTTMAPT | |
| SCHEMBL25307372 | 0.83 | ABCG2 (0.67) | ABCG2ABCB1ACHEHTTMAPT | |
| SCHEMBL5274120 | 0.79 | LMNA (0.67) | HTTMAPT | |
| SCHEMBL29393931 | 0.79 | ALDH1A1 (0.57) | ABCG2ABCB1ACHEHTTMAPT | |
| SCHEMBL25263149 | 0.78 | ABCG2 (0.61) | ABCG2ABCB1ACHEHTTMAPT | |
| SCHEMBL4618707 | 0.78 | MAOB (0.54) | ABCG2MAPT | |
| SCHEMBL30506423 | 0.77 | ALDH1A1 (0.58) | ABCG2ABCB1ACHEHTTMAPT | |
| SCHEMBL2768998 | 0.77 | GPR35 (0.65) | ABCG2ABCB1ACHEMAPT | |
| SCHEMBL5275641 | 0.77 | ACHE (0.67) | ABCG2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856084-A1 | CHROMEN-4-ONE DERIVATIVES | Merck Patent GmbH (DE) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006094601-A1 | CHROMEN-4-ONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2006-09-14 | — | — | WO | disclosed |