Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2522925 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL2526488 | 0.91 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL4465283 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL29612280 | 0.87 | CNR1 (0.35) | CNR1 | |
| Hydrochloric Acid SCHEMBL6523542 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL29612303 | 0.86 | BRD4 (0.32) | — | |
| Hydrochloric Acid SCHEMBL2524023 | 0.86 | BRD4 (0.32) | — | |
| Hydrochloric Acid SCHEMBL28753283 | 0.85 | KCNH2 (0.32) | CNR1CNR2HDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL4475684 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL29612294 | 0.82 | HSD11B1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2033975-B1 | Catalyst composition | BASELL POLYOLEFINE GMBH (DE) | 2014-05-14 | — | — | EP | disclosed |
| US-8039569-B2 | Polyethylene molding compositions for injection molding applications | BASELL POLYOLEFINE GMBH (DE) | 2011-10-18 | — | — | US | disclosed |
| EP-1874830-B1 | MOLDING COMPOSITION COMPRISING POLYETHYLENE FOR PREPARING FILMS AND PROCESS FOR PREPARING THE MOLDING COMPOSITION IN THE PRESENCE OF A MIXED CATALYST | BASELL POLYOLEFINE GMBH (DE) | 2010-10-20 | — | — | EP | disclosed |
| US-20090311453-A1 | Molding compostion comprsing polyethlene for preparing films and process for preparing the molding composition in the presence of a mixed catalyst | BASELL POLYOLEFINE GMBH (DE) | 2009-12-17 | — | — | US | disclosed |
| US-20090306324-A1 | Polyethylene molding compositions for injection molding applications | BASELL POLYOLEFINE GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| EP-2033975-A1 | Catalyst composition | Basell Polyolefine GmbH (DE) | 2009-03-11 | — | — | EP | disclosed |
| EP-1874831-B1 | POLYETHYLENE MOLDING COMPOSITIONS FOR INJECTION MOLDING APPLICATIONS | BASELL POLYOLEFINE GMBH (DE) | 2008-12-03 | — | — | EP | disclosed |
| EP-1874831-A1 | POLYETHYLENE MOLDING COMPOSITIONS FOR INJECTION MOLDING APPLICATIONS | Basell Polyolefine GmbH (DE) | 2008-01-09 | — | — | EP | disclosed |
| EP-1874830-A1 | MOLDING COMPOSITION COMPRISING POLYETHYLENE FOR PREPARING FILMS AND PROCESS FOR PREPARING THE MOLDING COMPOSITION IN THE PRESENCE OF A MIXED CATALYST | Basell Polyolefine GmbH (DE) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006114209-A1 | MOLDING COMPOSITION COMPRISING POLYETHYLENE FOR PREPARING FILMS AND PROCESS FOR PREPARING THE MOLDING COMPOSITION IN THE PRESENCE OF A MIXED CATALYST | BASELL POLYOLEFINE GMBH (DE) | 2006-11-02 | — | — | WO | disclosed |
| WO-2006114210-A1 | POLYETHYLENE MOLDING COMPOSITIONS FOR INJECTION MOLDING APPLICATIONS | BASELL POLYOLEFINE GMBH (DE) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090311453-A1 | Molding compostion comprsing polyethlene for preparing films and process for preparing the molding composition in the presence of a mixed catalyst | MAFG, PARG, MICOS13 | CNR1 1479/4885CNR2 2971/4885HDAC3 3306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.