Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079551 | 0.86 | GPR119 (0.46) | P2RX7GPR119FAAHKDM4EPKM | |
| SCHEMBL15939449 | 0.86 | GPR119 (0.46) | P2RX7GPR119FAAHKDM4EPKM | |
| SCHEMBL24493286 | 0.83 | GPR119 (0.48) | GPR119FAAH | |
| SCHEMBL22776955 | 0.82 | USP30 (0.50) | P2RX7GPR119FAAHKDM4EPKM | |
| SCHEMBL31583431 | 0.81 | ALDH1A1 (0.42) | GPR119FAAHKDM4EPKM | |
| SCHEMBL31173862 | 0.81 | FAAH (0.50) | GPR119FAAHKDM4EPKM | |
| SCHEMBL31173859 | 0.81 | FAAH (0.50) | GPR119FAAHKDM4EPKM | |
| SCHEMBL16012151 | 0.81 | FAAH (0.50) | GPR119FAAHKDM4EPKM | |
| SCHEMBL31747273 | 0.79 | GPR119 (0.50) | GPR119FAAHKDM4EPKM | |
| SCHEMBL2575742 | 0.78 | DDB1 (0.56) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436966-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2024-10-02 | — | — | EP | disclosed |
| WO-2023097031-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2023-06-01 | — | — | WO | disclosed |