SCHEMBL31173859

SCHEMBL31173859

CC(C)(C)OC(=O)N1CCC(CCCn2cc(Br)cn2)CC1

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 1/20 0.50
▸ GPR119 Q8TDV5 14/20 0.48
▸ KDM4E B2RXH2 1/20 0.44
▸ PKM P14618 1/20 0.44
▸ IDO1 P14902 1/20 0.43
▸ TDO2 P48775 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31173862 1.00 FAAH (0.50) FAAHGPR119KDM4EPKMIDO1
SCHEMBL29079551 0.94 GPR119 (0.46) FAAHGPR119KDM4EPKMIDO1
SCHEMBL1581892 0.88 FPR2 (0.48) FAAHGPR119KDM4EPKMIDO1
SCHEMBL16012151 0.86 FAAH (0.50) FAAHGPR119KDM4EPKM
SCHEMBL31747273 0.84 GPR119 (0.50) FAAHGPR119KDM4EPKM
SCHEMBL16012381 0.83 ALDH1A1 (0.52) FAAHGPR119KDM4EPKM
SCHEMBL1581610 0.82 CHRM2 (0.42) GPR119
SCHEMBL25269372 0.81 P2RX7 (0.47) FAAHGPR119KDM4EPKM
SCHEMBL15939449 0.81 GPR119 (0.46) FAAHGPR119KDM4EPKM
SCHEMBL31173852 0.79 GPR119 (0.58) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676929-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2026-01-14 — — EP disclosed
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 — — WO disclosed
EP-4667467-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2025-12-24 — — EP disclosed
WO-2024188906-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2024-09-19 — — WO disclosed
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