Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24493212 | 0.90 | GPR119 (0.48) | GPR119FAAH | |
| SCHEMBL29650131 | 0.90 | GPR119 (0.41) | GPR119FAAHCETP | |
| SCHEMBL15939449 | 0.83 | GPR119 (0.46) | GPR119FAAH | |
| SCHEMBL25269372 | 0.83 | P2RX7 (0.47) | GPR119FAAH | |
| SCHEMBL29079551 | 0.83 | GPR119 (0.46) | GPR119FAAH | |
| SCHEMBL24493084 | 0.80 | ACHE (0.40) | — | |
| SCHEMBL22719074 | 0.80 | DDB1 (0.53) | GPR119 | |
| SCHEMBL31173862 | 0.78 | FAAH (0.50) | GPR119FAAH | |
| SCHEMBL31173859 | 0.78 | FAAH (0.50) | GPR119FAAH | |
| SCHEMBL16012151 | 0.78 | FAAH (0.50) | GPR119FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745278-A | Enzyme inhibitors | 卡尔维斯塔制药有限公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2022118016-A2 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2022-06-09 | — | — | WO | disclosed |