Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14038235 | 0.83 | ALOX15 (0.55) | ALDH1A1ALOX15LMNANPSR1L3MBTL1 | |
| SCHEMBL25269324 | 0.83 | ALDH1A1 (0.41) | ALDH1A1ALOX15LMNANPSR1L3MBTL1 | |
| SCHEMBL2825471 | 0.81 | RAB9A (0.50) | ALDH1A1ALOX15LMNANPSR1L3MBTL1 | |
| SCHEMBL8654020 | 0.80 | ALOX15 (0.57) | ALDH1A1ALOX15LMNANPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL2825470 | 0.80 | RAB9A (0.49) | ALDH1A1ALOX15LMNANPSR1L3MBTL1 | |
| SCHEMBL2825362 | 0.79 | ALDH1A1 (0.44) | ALDH1A1ALOX15LMNANPSR1L3MBTL1 | |
| SCHEMBL2823116 | 0.79 | ALDH1A1 (0.38) | ALDH1A1ALOX15LMNANPSR1L3MBTL1 | |
| SCHEMBL14012153 | 0.79 | LMNA (0.38) | ALDH1A1ALOX15LMNANPSR1L3MBTL1 | |
| SCHEMBL2825371 | 0.75 | HRH3 (0.45) | ALDH1A1L3MBTL1HRH3KDM4EMAPK1 | |
| SCHEMBL3400738 | 0.75 | MEN1 (0.43) | ALDH1A1ALOX15L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323599-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-4192831-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |