Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920362 | 0.79 | PKM (0.64) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL25277596 | 0.78 | F2 (0.52) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL7301521 | 0.78 | PKM (0.61) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL25228450 | 0.76 | ALDH1A1 (0.52) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL25227041 | 0.75 | DDAH1 (0.47) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL25223096 | 0.75 | CA12 (0.58) | ALDH1A1GAAPTGS2CA1CA2 | |
| SCHEMBL1945898 | 0.73 | F2 (0.56) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL6102081 | 0.73 | F2 (0.61) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL25227079 | 0.73 | CYP2A6 (0.40) | ALDH1A1GAAKMT2AMMP2MMP1 | |
| SCHEMBL7310589 | 0.73 | F2 (0.56) | F2PRSS1PRSS2PRSS3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240409506-A1 | Compositions and Methods for Labeling of Thioethers | UNIV EMORY (US) | 2024-12-12 | — | — | US | claimed |
| WO-2023115020-A2 | COMPOSITIONS AND METHODS FOR LABELING OF THIOETHERS | EMORY UNIVERSITY (US) | 2023-06-22 | — | — | WO | claimed |
| US-20240409506-A1 | Compositions and Methods for Labeling of Thioethers | UNIV EMORY (US) | 2024-12-12 | — | — | US | disclosed |
| WO-2023115020-A2 | COMPOSITIONS AND METHODS FOR LABELING OF THIOETHERS | EMORY UNIVERSITY (US) | 2023-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409506-A1 | Compositions and Methods for Labeling of Thioethers | MGMT, PTMS, TST | F2 788/4885PRSS1 1877/4885PRSS2 1310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.