Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 6/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653955 | 0.83 | F2 (0.37) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL6920362 | 0.79 | PKM (0.64) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL7834461 | 0.79 | CA12 (0.48) | GAACA1CA2CA9CA12 | |
| SCHEMBL7833337 | 0.78 | SOS1 (0.55) | ALDH1A1KMT2ACA1CA2MMP1 | |
| SCHEMBL22302 | 0.78 | F2 (0.52) | F2PRSS1PRSS2PRSS3HPGD | |
| SCHEMBL7301521 | 0.78 | PKM (0.61) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL11868737 | 0.78 | KEAP1 (0.48) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL25513051 | 0.78 | PKM (0.47) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL9870656 | 0.77 | DRD1 (0.39) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL7465466 | 0.77 | POLB (0.59) | F2PRSS1PRSS2PRSS3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10287801-A | — | — | None | — | — | JP | disclosed |
| US-12139461-B1 | Piperidine compounds as PDE5 inhibitors | KING SAUD UNIVERSITY (SA) | 2024-11-12 | — | — | US | disclosed |
| US-20110130383-A1 | Use of Ion Channel Modulators in the Prophylaxis and Treatment of Inflammatory and Immunological Diseases | LECTUS THERAPEUTICS LIMITED (GB) | 2011-06-02 | — | — | US | disclosed |
| US-20090318423-A1 | Ion Channel Modulators & Uses Thereof | LECTUS THERAPEUTICS LIMITED (GB) | 2009-12-24 | — | — | US | disclosed |
| EP-2069309-A1 | ION CHANNEL MODULATORS&USES THEREOF | Lectus Therapeutics Limited (GB) | 2009-06-17 | — | — | EP | disclosed |
| EP-2066317-A2 | USE OF ION CHANNEL MODULATORS IN THE PROPHYLAXIS AND TREATMENT OF INFLAMMATORY AND IMMUNOLOGICAL DISEASES | Lectus Therapeutics Limited (GB) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008038053-A1 | ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2008-04-03 | — | — | WO | disclosed |
| WO-2008038051-A2 | USE OF ION CHANNEL MODULATORS IN THE PROPHYLAXIS AND TREATMENT OF INFLAMMATORY AND IMMUNOLOGICAL DISEASES | LECTUS THERAPEUTICS LIMITED (GB) | 2008-04-03 | — | — | WO | disclosed |
| US-7030274-B2 | Process for the production of carbodiimide modified organic isocyanates | BAYER MATERIALSCIENCE LLC (US) | 2006-04-18 | — | — | US | disclosed |
| US-20050282993-A1 | Process for the production of carbodiimide modified organic isocyanates | COVESTRO LLC | 2005-12-22 | — | — | US | disclosed |
| EP-0172379-B1 | MATERIAL FOR ORTHOPAEDIC BANDAGES | BAYER AG (DE) | 1989-04-19 | — | — | EP | disclosed |
| EP-0132675-B1 | PREPARATIONS OF POLYISOCYNATE CONTAINING REVERSIBLY BLOCKED CATALYSTS, PROCESS FOR THEIR PRODUCTION, THEIR USE IN THE PRODUCTION OF POLYURETHANES, AND ADDITION PRODUCTS OF SULFONYLISOCYANATES ON CATALYSTS WITH A STRUCTURE OF CARBOXYLATES OF TIN II OR IV | BAYER AG (DE) | 1988-12-07 | — | — | EP | disclosed |
| EP-0232541-A2 | Polyisocyanate compositions containing latent tin-catalysts, their use in the preparation of polyurethane resins and reaction products of sulfonyl isocyanates with selected tin compounds | BAYER AG (DE) | 1987-08-19 | — | — | EP | disclosed |
| US-4638795-A | FOR MEDICAL AND VETERINARY USE; BASED ON POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DE) | 1987-01-27 | — | — | US | disclosed |
| US-4614785-A | TERTIARY PHOSPHINE OR PERALKYLATED PHOSPHORUS ACID TRIAMIDE CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-30 | — | — | US | disclosed |
| EP-0173252-A2 | Process for the preparation of oligomeric polyisocyanates and their use in the preparation of polyurethane plastics | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0172379-A1 | Material for orthopaedic bandages | BAYER AG (DE) | 1986-02-26 | — | — | EP | disclosed |
| EP-0132675-A2 | Preparations of polyisocynate containing reversibly blocked catalysts, process for their production, their use in the production of polyurethanes, and addition products of sulfonylisocyanates on catalysts with a structure of carboxylates of tin II or IV | BAYER AG (DE) | 1985-02-13 | — | — | EP | disclosed |
| US-4282212-A | Immune-stimulating 1-(N-acylcarbamoyl)-2-cyanoaziridines | BOEHRINGER MANNHEIM GMBH (DE) | 1981-08-04 | — | — | US | disclosed |
| US-3971740-A | DYES FOR POLYESTER FIBERS | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12139461-B1 | Piperidine compounds as PDE5 inhibitors | PDE5A, PDE3A, PDE2A | F2 4664/4885PRSS1 2494/4885PRSS2 3160/4885 |
| US-20090318423-A1 | Ion Channel Modulators & Uses Thereof | KCNH3, KCNN3, KCNH2 | F2 2497/4885PRSS1 1564/4885PRSS2 1883/4885 |
| US-20110130383-A1 | Use of Ion Channel Modulators in the Prophylaxis and Treatment of Inflammatory and Immunological Diseases | HCAR2, HCAR1, SCN7A | F2 1383/4885PRSS1 1235/4885PRSS2 1257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.