Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26508543 | 0.86 | KDM4E (0.52) | KIF11MAOAKDM4EALDH1A1RAB9A | |
| SCHEMBL7456837 | 0.78 | MAOB (0.73) | KIF11MAOAMAOBPRKCZ | |
| SCHEMBL26509584 | 0.77 | ALDH1A1 (0.48) | KDM4EALDH1A1L3MBTL1GAA | |
| SCHEMBL16088363 | 0.76 | MAOA (0.53) | KIF11MAOAKDM4EL3MBTL1MAOB | |
| SCHEMBL23052081 | 0.73 | ALDH1A1 (0.70) | KIF11MAOAKDM4EALDH1A1RAB9A | |
| SCHEMBL23052318 | 0.73 | ALDH1A1 (0.70) | KIF11MAOAKDM4EALDH1A1RAB9A | |
| SCHEMBL26508522 | 0.72 | SMN1; SMN2 (0.45) | KDM4EALDH1A1RAB9ACASP3SMN1; SMN2 | |
| SCHEMBL5058846 | 0.72 | L3MBTL1 (0.59) | MAOAKDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL28736359 | 0.71 | MAOA (0.64) | MAOAMAOBCA1CA2 | |
| SCHEMBL7461031 | 0.70 | MAOB (0.73) | KIF11MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12473305-B2 | Pyrazole boronic acid compound, pharmaceutical composition containing same, and uses thereof | BEIJING SONGRUN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2025-11-18 | — | — | US | disclosed |
| EP-4201941-B1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | BEIJING SONGRUN PHARMACEUTICAL TECH CO LTD (CN) | 2025-11-05 | — | — | EP | disclosed |
| US-20230322816-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | BEIJING SONGRUN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-10-12 | — | — | US | disclosed |
| CN-114075227-B | Pyrazole boric acid compound, pharmaceutical composition containing pyrazole boric acid compound and application of pyrazole boric acid compound and pharmaceutical composition | 北京嵩润医药科技有限责任公司 | 2023-07-04 | — | — | CN | disclosed |
| EP-4201941-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | Beijing Songrun Pharmaceutical Technology Co., Ltd. (CN) | 2023-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12473305-B2 | Pyrazole boronic acid compound, pharmaceutical composition containing same, and uses thereof | PSMB11, PSMB7, PSMC5 | KIF11 1930/4885MAOA 1618/4885KDM4E 2668/4885 |
| US-20230322816-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | PSMB11, PSMB7, PSMC5 | KIF11 1930/4885MAOA 1618/4885KDM4E 2668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.